ArticleScientific reports2020
Transdiagnostic Phenotyping Reveals a Host of Metacognitive Deficits Implicated in Compulsivity.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 48 papers.
What it found
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Who cites it
48 citing papers in PubMed, 111 citations in OpenAlex.
- The relationship between apathy and impulsivity in large population samples.Scientific reports · 2021Trial
- Cognitive arbitration between candidate dimensions of psychopathology.Molecular psychiatry · 2026Article
- Human approach-avoidance conflict behaviour relates to transdiagnostic psychiatric symptom dimensions.Translational psychiatry · 2026Article
- Gender and anxiety reveal distinct computational sources of underconfidence.Psychological medicine · 2026Article
- Protocol for a randomized trial to predict the efficacy of cognitive and behavioral interventions for symptoms of depression.Frontiers in psychiatry · 2026Article
- Inflammatory profiles of transdiagnostic symptom dimensions in healthy females.Brain, behavior, & immunity - health · 2025Article
- The metacognitive paradox of OCD: confidence is globally reduced but shows increased sensitivity to local evidence.Research square · 2025Article
- Active information sampling in health and disease.Neuroscience and biobehavioral reviews · 2025Review
- Article
- Computational characterization of metacognitive ability in subjective decision-making.bioRxiv : the preprint server for biology · 2025Article
- Distorted learning from local metacognition supports transdiagnostic underconfidence.Nature communications · 2025Article
- Understanding learning through uncertainty and bias.Communications psychology · 2025Review
- Metacognitive biases in anxiety-depression and compulsivity extend across perception and memory.PLOS mental health · 2025Article
- Web-browsing patterns reflect and shape mood and mental health.Nature human behaviour · 2025Article
- Neural correlates of uncertainty processing in psychosis spectrum disorder.Brain communications · 2025Article
- Differential influence of habit components on compulsive and problematic reward-seeking behavior.PLOS mental health · 2025Article
- No gender difference in confidence or metacognitive ability in perceptual decision-making.iScience · 2024Article
- Consistency within change: Evaluating the psychometric properties of a widely used predictive-inference task.Behavior research methods · 2024Article
- Information search under uncertainty across transdiagnostic psychopathology and healthy ageing.Translational psychiatry · 2024Article
- Compulsive avoidance in youths and adults with OCD: an aversive pavlovian-to-instrumental transfer study.Translational psychiatry · 2024Article
Corrections and comments
- Erratum issued
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Recent work suggests that obsessive-compulsive disorder (OCD) patients have a breakdown in the relationship between explicit beliefs (i.e. confidence about states) and updates to behaviour. The precise computations underlying this disconnection are unclear because case-control and transdiagnostic studies yield conflicting results. Here, a large online population sample (N = 437) completed a predictive inference task previously studied in the context of OCD. We tested if confidence, and its relationship to action and environmental evidence, were specifically associated with self-reported OCD symptoms or common to an array of psychiatric phenomena. We then investigated if a transdiagnostic approach would reveal a stronger and more specific match between metacognitive deficits and clinical phenotypes. Consistent with prior case-control work, we found that decreases in action-confidence coupling were associated with OCD symptoms, but also 5/8 of the other clinical phenotypes tested (8/8 with no correction applied). This non-specific pattern was explained by a single transdiagnostic symptom dimension characterized by compulsivity that was linked to inflated confidence and several deficits in utilizing evidence to update confidence. These data highlight the importance of metacognitive deficits for our understanding of compulsivity and underscore how transdiagnostic methods may prove a more powerful alternative over studies examining single disorders.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.