ReviewNutrition & diabetes2020
Chrononutrition in the management of diabetes.
Review in Nutrition & diabetes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 82 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of a Chrono Nutrition Intervention on Insulin Resistance in Adults With Type 2 Diabetes
Impact of Pasta Consumption Timing on Multiple Health Outcomes
Who cites it
82 citing papers in PubMed, 5 syntheses or guidelines pooled it, 155 citations in OpenAlex.
- Effects of intermittent fasting on HbA1c and weight in insulin versus oral hypoglycemic therapy-treated patients with type 2 diabetes mellitus: a systematic review and meta-analysis.Frontiers in nutrition · 2026Pooled it
- Meal frequency strategies for the management of type 2 diabetes subjects: A systematic review.PloS one · 2024Pooled it
- Distribution of energy intake across the day and weight loss: A systematic review and meta-analysis.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2023Pooled it
- Pooled it
- Chronotype Differences in Energy Intake, Cardiometabolic Risk Parameters, Cancer, and Depression: A Systematic Review with Meta-Analysis of Observational Studies.Advances in nutrition (Bethesda, Md.) · 2022Pooled it
- Chronobiological Factors Influencing Glycemic Control and Birth Outcomes in Gestational Diabetes Mellitus.Nutrients · 2024Trial
- Continuous Glucose Monitoring Metrics and Risks of Severe Hypoglycemia and Diabetic Ketoacidosis in Type 1 Diabetes: A Pooled Analysis.Diabetes care · 2026Article
- Targeting Habitual Fast Eating as a Modifiable Risk Factor for Type 2 Diabetes: A Propensity Score-Matched Analysis.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2026Article
- Real-Time Psychological Factors Using Ecological Momentary Assessment With Continuous Glucose Monitoring in Diabetes Mellitus: Scoping Review.JMIR diabetes · 2026Review
- Circadian Misalignment and Chrononutrition in Type 2 Diabetes: Mechanistic Insights and Translational Gaps.International journal of molecular sciences · 2026Review
- Article
- Maternal chrononutrition during pregnancy and the composition of intestinal and placental microbiota.BMC pregnancy and childbirth · 2026Article
- Association Between the Meal Timing of Dietary Flavonoids and Non-Alcoholic Fatty Liver Disease in U.S. Adults: An NHANES Analysis.Healthcare (Basel, Switzerland) · 2026Article
- The association of time-restricted eating and indices of organ-specific aging in relation to metabolic health and obesity.NPJ science of food · 2026Article
- Circulating Rhythmic Metabolites and Causal Risk of Type 2 Diabetes in Adults in the Canadian Longitudinal Study on Aging.Diabetes, obesity & metabolism · 2026Article
- A Novel Chronotype-Based Mediterranean Diet Pyramid: An Updated Representation by the Italian Society of Endocrinology (SIE) and the Italian Society of Dietetics and Clinical Nutrition (ADI).Current nutrition reports · 2026Review
- Plausible Obesity-Related Chronometabolic and Nutrigenetic Nexus Concerning Dinner Glycemic Index and theBiomolecules · 2026Article
- The Influence of Sleep and Diet on Human Peripheral Immunity and Chronic Health Conditions.Research (Washington, D.C.) · 2026Article
- Nutritional adaptation to circadian misalignment: implications for musculoskeletal health in modern lifestyles.Frontiers in nutrition · 2026Review
- The Role of Chronopsychiatry in Precision Medicine: Circadian Dysregulation as Diagnostic Marker and Therapeutic Target.Current sleep medicine reports · 2026Review
22 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Circadian rhythms are 24-h cycles regulated by endogeneous molecular oscillators called the circadian clock. The effects of diet on circadian rhythmicity clearly involves a relationship between factors such as meal timings and nutrients, known as chrononutrition. Chrononutrition is influenced by an individual's "chronotype", whereby "evening chronotypes" or also termed "later chronotype" who are biologically driven to consume foods later in the day. Research in this area has suggested that time of day is indicative of having an influence on the postprandial glucose response to a meal, therefore having a major effect on type 2 diabetes. Cross-sectional and experimental studies have shown the benefits of consuming meals early in the day than in the evening on postprandial glycaemia. Modifying the macronutrient composition of night meals, by increasing protein and fat content, has shown to be a simple strategy to improve postprandial glycaemia. Low glycaemic index (GI) foods eaten in the morning improves glycaemic response to a greater effect than when consumed at night. Timing of fat and protein (including amino acids) co-ingested with carbohydrate foods, such as bread and rice, can reduce glycaemic response. The order of food presentation also has considerable potential in reducing postprandial blood glucose (consuming vegetables first, followed by meat and then lastly rice). These practical recommendations could be considered as strategies to improve glycaemic control, rather than focusing on the nutritional value of a meal alone, to optimize dietary patterns of diabetics. It is necessary to further elucidate this fascinating area of research to understand the circadian system and its implications on nutrition that may ultimately reduce the burden of type 2 diabetes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.