Evidence map›Paper›PMID 32075940›Full record

ArticleRNA (New York, N.Y.)2020

PIWI-piRNA pathway-mediated transposable element repression in

Bryan B Teefy, Stefan Siebert, Jack F Cazet, Haifan Lin, Celina E Juliano

Open access · bronzeAbstract read
In one paragraph

Article in RNA (New York, N.Y.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Review
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  10. Review
  11. The Ancient Origin and Function of Germline Cysts.Results and problems in cell differentiation · 2024
    Article
  12. Review
  13. Review
  14. Small RNAs in Cnidaria: A review.Evolutionary applications · 2023
    Article
  15. Article
  16. Transposable element and host silencing activity in gigantic genomes.Frontiers in cell and developmental biology · 2023
    Article
  17. Transposon control as a checkpoint for tissue regeneration.Development (Cambridge, England) · 2022
    Article
  18. The Hippo pathway regulates axis formation and morphogenesis inProceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Bryan B TeefyDepartment of Molecular and Cellular Biology, University of California, Davis, California 95616, USA.ORCID 0000-0002-1982-1728
Stefan SiebertDepartment of Molecular and Cellular Biology, University of California, Davis, California 95616, USA.ORCID 0000-0001-8181-912X
Jack F CazetDepartment of Molecular and Cellular Biology, University of California, Davis, California 95616, USA.ORCID 0000-0002-7331-5631
Haifan LinDepartment of Cell Biology, Yale Stem Cell Center, Yale University School of Medicine, New Haven, Connecticut 06520, USA.ORCID 0000-0002-5374-9491
Celina E JulianoDepartment of Molecular and Cellular Biology, University of California, Davis, California 95616, USA.ORCID 0000-0003-4222-0987
University of California, Davis · USYale Cancer Center · US

Funding

UC Davis MCB T32 Administrative Supplement to Recognize Excellence in Diversity, Equity, Inclusion, and Accessibility (DEIA) MentorshipT32GM007377 · NIGMS · UNIVERSITY OF CALIFORNIA DAVIS · PI CHEDIN, FREDERIC LOUIS · 1985 to 2023
$9.9M
Identifying targets of the Piwi/piRNA pathway in stem cellsK01AG044435 · NIA · YALE UNIVERSITY · PI JULIANO, CELINA · 2014 to 2017
$475k
Acquisition of Covaris E220 and Sciclone G3 systems for high throughput sequencinS10OD010786 · OD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI COMAI, LUCA · 2012 to 2012
$311k
NIA NIH HHS K01 AG044435NIGMS NIH HHS T32 GM007377NIH HHS S10 OD010786
6 · The paper itself

Abstract

Transposable elements (TEs) can damage genomes, thus organisms use a variety of mechanisms to repress TE expression. The PIWI-piRNA pathway is a small RNA pathway that represses TE expression in the germline of animals. Here we explore the function of the pathway in the somatic stem cells of

Indexed as

AnimalsArgonaute ProteinsCell LineageDNA Transposable ElementsEctodermEndodermEpithelial CellsGene Expression Regulation, DevelopmentalGene SilencingHydraRNA InterferenceRNA, Small InterferingStem CellsArgonaute ProteinsDNA Transposable ElementsRNA, Small InterferingagingHydrapiRNAPIWIstem cellstransposable elements

Identifiers

PMID32075940
PMCPMC7161359
OpenAlexW3007141219

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.