Evidence map›Paper›PMID 32075835›Full record

Trial reportBMJ open2020

Recovery from recurrent depression with mindfulness-based cognitive therapy and antidepressants: a qualitative study with illustrative case studies.

Alice Tickell, Richard Byng, Catherine Crane, Felix Gradinger, Rachel Hayes, James Robson, Jessica Cardy, Alice Weaver, Nicola Morant, Willem Kuyken

Open access · goldAbstract readCase ReportsRandomized Controlled Trial
In one paragraph

Trial report in BMJ open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Role of primary care in depression relapse: a qualitative study.The British journal of general practice : the journal of the Royal College of General Practitioners · 2025
    Article
  6. Article
  7. Article
  8. The lived experience of depression: a bottom-up review co-written by experts by experience and academics.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2023
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Alice TickellDepartment of Psychiatry, University of Oxford, Oxford, UK.
Richard ByngPeninsula Medical School, Faculty of Health, University of Plymouth, Plymouth, UK.
Catherine CraneDepartment of Psychiatry, University of Oxford, Oxford, UK.
Felix GradingerPeninsula Medical School, Faculty of Health, University of Plymouth, Plymouth, UK.
Rachel HayesDepartment of Psychiatry, University of Oxford, Oxford, UK.
James RobsonDepartment of Education, University of Oxford, Oxford, UK.
Jessica CardyDepartment of Psychiatry, University of Oxford, Oxford, UK.
Alice WeaverDepartment of Psychiatry, University of Oxford, Oxford, UK.
Nicola MorantDepartment of Psychiatry, University College London, London, UK.ORCID 0000-0003-4022-8133
Willem KuykenDepartment of Psychiatry, University of Oxford, Oxford, UK willem.kuyken@psych.ox.ac.uk.ORCID 0000-0002-8596-5252
University of Oxford · GBUniversity of Plymouth · GBUniversity College London · GB

Funding

Wellcome TrustWellcome Trust 107496/Z/15/Z
6 · The paper itself

Abstract

objectivesThis study aimed to describe the recovery journeys of people with a history of recurrent depression who took part in a psychosocial programme designed to teach skills to prevent depressive relapse (mindfulness-based cognitive therapy (MBCT)), alongside maintenance antidepressant medication (ADM).

designA qualitative study embedded within a multicentre, single blind, randomised controlled trial (the PREVENT trial).

settingPrimary care urban and rural settings in the UK.

participants42 people who participated in the MBCT arm of the parent trial were purposively sampled to represent a range of recovery journeys.

interventionsMBCT involves eight weekly group sessions, with four refresher sessions offered in the year following the end of the programme. It was adapted to offer bespoke support around ADM tapering and discontinuation.

methodsWritten feedback and structured in-depth interviews were collected in the 2 years after participants undertook MBCT. Data were analysed using thematic analysis and case studies constructed to illustrate the findings.

resultsPeople with recurrent depression have unique recovery journeys that shape and are shaped by their pharmacological and psychological treatment choices. Their journeys typically include several over-arching themes: (1) beliefs about the causes of depression, both biological and psychosocial; (2) personal agency, including expectations about their role in recovery and treatment; (3) acceptance, both of depression itself and the recovery journey; (4) quality of life; (5) experiences and perspectives on ADM and ADM tapering-discontinuation; and (6) the role of general practitioners, both positive and negative.

conclusionsPeople with recurrent depression describe unique, complex recovery journeys shaped by their experiences of depression, treatment and interactions with health professionals. Understanding how several themes coalesce for each individual can both support their recovery and treatment choices as well as health professionals in providing more accessible, collaborative, individualised and empowering care. TRIAL REGISTRATION NUMBER: Clinical trial number ISRCTN26666654; post results.

Indexed as

MindfulnessAdultAgedAntidepressive AgentsAttitudeChronic DiseaseCognitive Behavioral TherapyDepressionFemaleGeneral PractitionersHumansMajor Depressive DisorderMaleMiddle AgedPrimary Health CarePsychotherapy, GroupAntidepressive Agentsantidepressantsdepression & mood disorderspsychological therapy

Identifiers

PMID32075835
PMCPMC7044862
OpenAlexW3007064923

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.