Evidence map›Paper›PMID 32075747›Full record

ArticleBiophysical journal2020

Partial Metal Ion Saturation of C2 Domains Primes Synaptotagmin 1-Membrane Interactions.

Sachin Katti, Sarah B Nyenhuis, Bin Her, David S Cafiso, Tatyana I Igumenova

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biophysical journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Solid-State NMR Study to Probe the Effects of Divalent Metal Ions (CaLangmuir : the ACS journal of surfaces and colloids · 2021
    Article
  3. Interference of pH buffer with PbMetallomics : integrated biometal science · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Sachin KattiDepartment of Biochemistry and Biophysics, Texas A&M University, College Station, Texas.
Sarah B NyenhuisDepartment of Chemistry and Biophysics Program, University of Virginia, Charlottesville, Virginia.
Bin HerDepartment of Biochemistry and Biophysics, Texas A&M University, College Station, Texas.
David S CafisoDepartment of Chemistry and Biophysics Program, University of Virginia, Charlottesville, Virginia.
Tatyana I IgumenovaDepartment of Biochemistry and Biophysics, Texas A&M University, College Station, Texas. Electronic address: tigumenova@tamu.edu.
Texas A&M University · USUniversity of Virginia · US

Funding

Structural Dynamics of the Exocytotic Fusion Machine in Neurons.P01GM072694 · NIGMS · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI KIESSLING, VOLKER · 2005 to 2021
$17.4M
Structural and Functional Studies of Protein Kinase C RegulationR01GM108998 · NIGMS · TEXAS A&M AGRILIFE RESEARCH · PI Tatyana I. Igumenova · 2014 to 2026
$3.3M
NIGMS NIH HHS P01 GM072694NIGMS NIH HHS R01 GM108998
6 · The paper itself

Abstract

Synaptotagmin 1 (Syt1) is an integral membrane protein whose phospholipid-binding tandem C2 domains, C2A and C2B, act as Ca

Indexed as

C2 DomainsSynaptotagmin ICalciumIonsPhosphatidylserinesProtein BindingSynaptotagminsCalciumIonsPhosphatidylserinesSynaptotagmin ISynaptotagmins

Identifiers

PMID32075747
PMCPMC7091512
OpenAlexW3004759626

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.