ArticleBMC medical ethics2020
Structural racism in precision medicine: leaving no one behind.
Article in BMC medical ethics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05697198 (PRospective REgistry of Advanced Stage CancER), which is not on this map. Cited by 59 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
PRospective REgistry of Advanced Stage CancER (PREFER) Patients to Assess Prevalence of Actionable Biomarkers and Driver Mutations Using the OmniSeq Test and Creation of a Biobank from Community Cancer Clinics in the United States to Address Disparities in Precision Medicine
Who cites it
59 citing papers in PubMed, 7 syntheses or guidelines pooled it, 121 citations in OpenAlex.
- Equity and Cancer Survival Among Veterans Health Administration Patients: A Systematic Review and Meta-Analysis.JAMA network open · 2026Pooled it
- Balancing benefits and burdens: a systematic review on ethical and social dimensions of gene and cell therapies for hereditary blood diseases.BMC medical ethics · 2025Pooled it
- Structural racism as a leading cause of racial disparities in breast cancer quality of care outcomes: a systematic review.Frontiers in oncology · 2025Pooled it
- Mind the NIH-Funding Gap: Structural Discrimination in Physical Health-Related Research for Cognitively Able Autistic Adults.Journal of autism and developmental disorders · 2024Pooled it
- Big Data and Digitalization in Dentistry: A Systematic Review of the Ethical Issues.International journal of environmental research and public health · 2020Pooled it
- Pooled it
- Pooled it
- Addressing the knowledge and recruitment gap in Alzheimer's disease and precision medicine research among Native people: an innovative randomized controlled trial.Ethnicity & health · 2025Trial
- The Continuity Trap in Data Science Health Research.Journal of medical Internet research · 2026Article
- Aerobic Exercise Response Variation and Cardiorespiratory Fitness in Adults with Coronary Heart Disease: An SDir Meta-Analysis of Randomized Controlled Trials.Journal of cardiovascular development and disease · 2026Review
- The North Carolina PARTNERS Program: Preparing Undergraduates for Research Careers in Cancer Prevention, Causes, and Treatment in Traditionally Underrepresented Populations.Journal of cancer education : the official journal of the American Association for Cancer Education · 2026Article
- SPARK: making ethical and societal tensions explicit in AI-supported precision medicine education.BMC medical ethics · 2026Article
- Learning Health Systems, Equity, and Bounded Justice: A Critical Scoping Review.Learning health systems · 2026Article
- Developing a Suicide Risk Prediction Algorithm Using Electronic Health Record Data in Mental Health Care: Real-World Case Study.JMIR medical informatics · 2026Article
- What Is Fair? Defining Fairness in Machine Learning for Health.Statistics in medicine · 2025Review
- Trusted partners, community priorities, and data protections: requirements for precision medicine research with Alaska Native peoples.Journal of community genetics · 2025Article
- Health Equity and Artificial Intelligence in Nephrology.Clinical journal of the American Society of Nephrology : CJASN · 2025Article
- Identifying High-Priority Ethical Challenges for Precision Emergency Medicine: Nominal Group Study.JMIR formative research · 2025Article
- Multi-omics approaches for understanding gene-environment interactions in noncommunicable diseases: techniques, translation, and equity issues.Human genomics · 2025Review
- From one size fits all to a tailored approach: integrating precision medicine into medical education.BMC medical education · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPrecision medicine (PM) is an emerging approach to individualized care. It aims to help physicians better comprehend and predict the needs of their patients while effectively adopting in a timely manner the most suitable treatment by promoting the sharing of health data and the implementation of learning healthcare systems. Alongside its promises, PM also entails the risk of exacerbating healthcare inequalities, in particular between ethnoracial groups. One often-neglected underlying reason why this might happen is the impact of structural racism on PM initiatives. Raising awareness as to how structural racism can influence PM initiatives is paramount to avoid that PM ends up reproducing the pre-existing health inequalities between different ethnoracial groups and contributing to the loss of trust in healthcare by minority groups. MAIN BODY: We analyse three nodes of a process flow where structural racism can affect PM's implementation. These are: (i) the collection of biased health data during the initial encounter of minority groups with the healthcare system and researchers, (ii) the integration of biased health data for minority groups in PM initiatives and (iii) the influence of structural racism on the deliverables of PM initiatives for minority groups. We underscore that underappreciation of structural racism by stakeholders involved in the PM ecosystem can be at odds with the ambition of ensuring social and racial justice. Potential specific actions related to the analysed nodes are then formulated to help ensure that PM truly adheres to the goal of leaving no one behind, as endorsed by member states of the United Nations for the 2030 Agenda for Sustainable Development.
conclusionStructural racism has been entrenched in our societies for centuries and it would be naïve to believe that its impacts will not spill over in the era of PM. PM initiatives need to pay special attention to the discriminatory and harmful impacts that structural racism could have on minority groups involved in their respective projects. It is only by acknowledging and discussing the existence of implicit racial biases and trust issues in healthcare and research domains that proper interventions to remedy them can be implemented.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.