Evidence map›Paper›PMID 32075581›Full record

ArticleBMC infectious diseases2020

The association between climate, geography and respiratory syncitial virus hospitalizations among children in Ontario, Canada: a population-based study.

Dhenuka Radhakrishnan, Alexandra Ouedraogo, Salimah Z Shariff, J Dayre McNally, Eric I Benchimol, Kristin K Clemens

Open access · goldAbstract read
In one paragraph

Article in BMC infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Observational
  5. Article
  6. Article
  7. Article
  8. Phylogenetic and phylodynamic analysis of respiratory syncytial virus strains circulating in children less than five years of age in Karachi-Pakistan.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2024
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  12. Review
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  14. Review
  15. Molecular Mechanisms of RSV and Air Pollution Interaction: A Scoping Review.International journal of molecular sciences · 2022
    Article
  16. Influences of environmental exposures on preterm lung disease.Expert review of respiratory medicine · 2021
    Review
  17. Article
  18. Article
  19. Clinico demographic profiling of theJournal of family medicine and primary care · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Dhenuka RadhakrishnanChildren's Hospital of Eastern Ontario Research Institute, 401 Smyth Road, Ottawa, ON, K1H 8L1, Canada. dhenuka@gmail.com.
Alexandra OuedraogoICES, Toronto, Ontario, Canada.
Salimah Z ShariffICES, Toronto, Ontario, Canada.
J Dayre McNallyChildren's Hospital of Eastern Ontario Research Institute, 401 Smyth Road, Ottawa, ON, K1H 8L1, Canada.
Eric I BenchimolChildren's Hospital of Eastern Ontario Research Institute, 401 Smyth Road, Ottawa, ON, K1H 8L1, Canada.
Kristin K ClemensICES, Toronto, Ontario, Canada. kristin.clemens@sjhc.london.on.ca.
Institute for Clinical Evaluative Sciences · CAChildren's Hospital of Eastern Ontario · CA

Funding

Academic Medical Organization of Southwestern Ontario N/AInstitute for Clinical Evaluative Sciences N/A
6 · The paper itself

Abstract

backgroundRespiratory syncytial virus (RSV) infection is a major cause of hospitalization in young children in Canada, despite routine immunoprophylaxis in those with medical risk factors. We aimed to determine if cold temperatures are associated with RSV hospitalization.

methodsWe conducted a population-based nested case-control study of children in Ontario, Canada, using health administrative data. We compared children hospitalized for RSV between September 1, 2011 and August 31, 2012 to age and sex matched controls. We used multivariable logistic regression to identify associations between minimum daily temperature and RSV hospitalizations with adjustment for sociodemographic and environmental factors.

resultsWe identified 1670 children with RSV hospitalizations during the study period and 6680 matched controls. Warmer temperatures (OR = 0.94, 95%CI: 0.93, 0.95) were associated with lower odds of RSV hospitalization. Southern ecozone (OR = 1.6, 95%CI: 1.2, 2.1), increased ozone concentration (OR = 1.03, 95%CI: 1.01, 1.06) and living in a lower income neighbourhood (OR = 1.3, 95%CI: 1.1, 1.5) significantly increased the odds of RSV hospitalization, as did living in a household with a larger number of siblings in a sub-cohort of children (OR = 1.34, 95%CI: 1.26, 1.41).

conclusionsIn Ontario, the likelihood of having an RSV hospitalization is associated with colder temperature exposures and socioeconomic factors.

Indexed as

Case-Control StudiesFemaleHospitalizationHumansImmunizationInfantInfant, NewbornLogistic ModelsMaleOntarioPovertyRespiratory Syncytial Virus InfectionsRisk FactorsSocioeconomic FactorsTemperatureWeatherChildrenHospital admissionRespiratory syncytial virusTemperature

Identifiers

PMID32075581
PMCPMC7031991
OpenAlexW3007903485

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.