ArticleEnvironmental health and preventive medicine2020
The relationship between metabolic syndrome and the incidence of colorectal cancer.
Article in Environmental health and preventive medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 5 of them syntheses that pooled it.
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Who cites it
32 citing papers in PubMed, 5 syntheses or guidelines pooled it, 50 citations in OpenAlex.
- Obstructive Sleep Apnea and Colorectal Cancer: A Systematic Review and Meta-Analysis.Journal of gastrointestinal cancer · 2023Pooled it
- The metabolic syndrome and its components as prognostic factors in colorectal cancer: A meta-analysis and systematic review.Journal of gastroenterology and hepatology · 2023Pooled it
- Correlation between pancreatic cancer and metabolic syndrome: A systematic review and meta-analysis.Frontiers in endocrinology · 2023Pooled it
- Metabolic syndrome and the risk of colorectal cancer: a systematic review and meta-analysis.International journal of colorectal disease · 2021Pooled it
- The association of Metabolic Syndrome and its Components with the Incidence and Survival of Colorectal Cancer: A Systematic Review and Meta-analysis.International journal of biological sciences · 2021Pooled it
- Association Between Colorectal Neoplasia and Subclinical Coronary Atherosclerosis in Asymptomatic Individuals.Journal of Korean medical science · 2026Article
- Associations between Metabolic Syndrome Indicators and Colon Polyps: A Mendelian Randomization Study.Endocrinology and metabolism (Seoul, Korea) · 2026Article
- Association between insulin resistance biomarkers and metastatic prognosis in treatment-naïve colorectal cancer patients: a pilot study.BMC cancer · 2025Article
- Risk of colorectal cancer in kidney transplant recipients and patients with end-stage renal disease undergoing hemodialysis.The Korean journal of internal medicine · 2025Article
- Association of triglyceride-glucose related indices with colorectal cancer risk among the US population: a cross-sectional study.BMC cancer · 2025Article
- Facial Appearance and Markers of Cardiometabolic Risk in Healthy Adult Men.Archives of sexual behavior · 2025Article
- Article
- Genetic prediction of the relationship between metabolic syndrome and colorectal cancer risk: a Mendelian randomization study.Diabetology & metabolic syndrome · 2024Article
- Association between Atherosclerosis and High-Risk Colorectal Adenomas based on Cardio-Ankle Vascular Index and Ankle-Brachial Index.The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2024Article
- Association between Surrogate Markers of Insulin Resistance and the Incidence of Colorectal Cancer in Korea: A Nationwide Population-Based Study.Journal of clinical medicine · 2024Article
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- Article
- Integrating machine learning and nontargeted plasma lipidomics to explore lipid characteristics of premetabolic syndrome and metabolic syndrome.Frontiers in endocrinology · 2024Article
- Nuclear Receptor PPARα as a Therapeutic Target in Diseases Associated with Lipid Metabolism Disorders.Nutrients · 2023Review
- Prevalence of Metabolic Syndrome Based on the Dietary Habits and Physical Activity of Korean Women Cancer Survivors.Foods (Basel, Switzerland) · 2023Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThis study evaluated the incidence of colorectal cancer (CRC) according to the number of metabolic syndrome (MetS) components.
methodsUsing health checkup and insurance claims data of 6,365,409 subjects, the occurrence of CRC according to stage of MetS by sex was determined from the date of the health checkup in 2009 until December 31, 2018.
resultsCumulative incidence rates (CIR) of CRC in men and women was 3.9 and 2.8 per 1000 (p < 0.001), respectively. CIR of CRC for the normal, pre-MetS, and MetS groups in men was 2.6, 3.9, and 5.5 per 1000 (p < 0.001) and CIR in women was 2.1, 2.9, and 4.5 per 1000 (p < 0.001), respectively. Compared with the normal group, the hazard ratio (HR) of CRC for the pre-MetS group was 1.25 (95% CI 1.17-1.33) in men and 1.09 (95% CI 1.02-1.17) in women, and the HR of CRC for the MetS group was 1.54 (95% CI 1.43-1.65) in men and 1.39 (95% CI 1.26-1.53) in women after adjustment.
conclusionsWe found that MetS is a risk factor for CRC in this study. Therefore, the prevention and active management of MetS would contribute to the prevention of CRC.
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