Evidence map›Paper›PMID 32075253›Full record

ArticleMolecules (Basel, Switzerland)2020

Cytotoxic Activity of Organotin(IV) Derivatives with Triazolopyrimidine Containing Exocyclic Oxygen Atoms.

Alessandro Attanzio, Simone D'Agostino, Rosalia Busà, Anna Frazzitta, Simona Rubino, Maria Assunta Girasolo, Piera Sabatino, Luisa Tesoriere

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 43 citations in OpenAlex.

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  4. Mitochondrial apoptosis and GScientific reports · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Alessandro AttanzioDepartment of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, Parco d'Orleans II, Viale delle Scienze-Pad., 16-90128 Palermo, Italy.ORCID 0000-0002-6622-028X
Simone D'AgostinoDepartment of Chemistry "G. Ciamician", University of Bologna, via F. Selmi 2, 40126 Bologna, Italy.ORCID 0000-0003-3065-5860
Rosalia BusàDepartment of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, Parco d'Orleans II, Viale delle Scienze-Pad., 16-90128 Palermo, Italy.ORCID 0000-0002-7546-7209
Anna FrazzittaDepartment of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, Parco d'Orleans II, Viale delle Scienze-Pad., 16-90128 Palermo, Italy.
Simona RubinoDepartment of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, Parco d'Orleans II, Viale delle Scienze-Pad., 16-90128 Palermo, Italy.ORCID 0000-0002-8911-1414
Maria Assunta GirasoloDepartment of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, Parco d'Orleans II, Viale delle Scienze-Pad., 16-90128 Palermo, Italy.ORCID 0000-0001-8122-4521
Piera SabatinoDepartment of Chemistry "G. Ciamician", University of Bologna, via F. Selmi 2, 40126 Bologna, Italy.
Luisa TesoriereDepartment of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, Parco d'Orleans II, Viale delle Scienze-Pad., 16-90128 Palermo, Italy.ORCID 0000-0002-7980-7530
University of Palermo · ITUniversity of Bologna · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study cytotoxicity of organotin(IV) compounds with 1,2,4-triazolo[1,5-

Indexed as

Gene Expression Regulation, NeoplasticApoptosisCell SurvivalCyclin-Dependent Kinase Inhibitor p21CytotoxinsDrug DesignG1 Phase Cell Cycle CheckpointsG2 Phase Cell Cycle CheckpointsHCT116 CellsHep G2 CellsHumansInhibitory Concentration 50MCF-7 CellsMembrane Potential, MitochondrialMitochondrial MembranesOrganotin CompoundsCyclin-Dependent Kinase Inhibitor p21CytotoxinsOrganotin CompoundsPyrimidinesReactive Oxygen SpeciesTriazolesTumor Suppressor Protein p53apoptosiscrystal structurein vitro anticancer activitymetallodrugsorganotin(IV)triazolopyrimidine

Identifiers

PMID32075253
PMCPMC7070731
OpenAlexW3006323190

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.