ArticleInternational journal of environmental research and public health2020
Severe Oral Mucositis in Pediatric Cancer Patients: Survival Analysis and Predictive Factors.
Article in International journal of environmental research and public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.
- Prevention and the treatment of oral mucositis: the efficacy of sodium bicarbonate vs other agents: a systematic review.BMC oral health · 2023Pooled it
- The parents voice on oral health care from two paediatric oncology units.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026Observational
- Impact of oral mucositis treated by photobiomodulation protocol on the quality of life of pediatric oncology patients with acute lymphoblastic leukemia.Lasers in medical science · 2026Article
- Oral Mucositis in Oncopediatric Patients: MTX and MMP-1, MMP-8, MMP-13 Gene Polymorphisms.Oral diseases · 2026Article
- Nurses' experiences and perceived needs in managing chemotherapy-induced mucositis in pediatric oncology: A qualitative exploratory study toward developing an empowerment-based nursing model.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Risk Factors for Oral Mucositis in Pediatric Oncology Patients Undergoing Chemotherapy: A Prospective Cohort.Asian Pacific journal of cancer prevention : APJCP · 2025Article
- The effect of honey in oral care intervention against chemotherapy-induced mucositis in pediatric cancer patients: a pilot study.BMC complementary medicine and therapies · 2024Article
- The Effect of Oral Care Intervention in Mucositis Management Among Pediatric Cancer Patients: An Updated Systematic Review.Journal of multidisciplinary healthcare · 2024Review
- The Study Progress and Analysis of Preventive Measures of Nursing Care for Chemotherapy-Induced Oral Mucositis in Pediatric Patients with Hematologic Malignancies: A Retrospective Study.Journal of multidisciplinary healthcare · 2024Article
- Nursing care approaches to oral mucositis in pediatric oncology clinics: a cross-sectional study from Türkiye.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023Article
- Article
- Prevention and Treatment of Oral Complications in Hematologic Childhood Cancer Patients: An Update.Children (Basel, Switzerland) · 2022Review
- Incidence and risk factors for oral mucositis in pediatric patients receiving chemotherapy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021Article
- Impact of severe oral mucositis in pediatric cancer patients on resource utilization and cancer treatment plans.International journal of clinical pharmacy · 2021Article
- Integrated oral care contributes positively to the course of treatment of oncopediatric patients.European journal of pediatrics · 2021Article
- Life-threatening oral mucositis following chemotherapy in a pediatric patient.Clinical case reports · 2021Article
- The incidence of severe oral mucositis and its occurrence sites in pediatric oncologic patients.Medicina oral, patologia oral y cirugia bucal · 2021Observational
- Severe oral mucositis relating to pain and worse oral condition among patients with solid tumors undergoing treatment with FOLFIRI and 5-FU: a retrospective study.Sao Paulo medical journal = Revista paulista de medicinaArticle
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This paper investigates the occurrence of severe oral mucositis and associated factors in blood and solid cancer pediatric patients subjected to cancer treatment, using a survival analysis. A longitudinal, descriptive, observational and inductive study of 142 pediatric patients aged from 0 to 19 years was conducted from 2013 to 2017. Data were collected using a form to record the sociodemographic characteristics and health-related aspects of patients and the modified Oral Assessment Guide (OAG). Survival analysis was performed using the Kaplan-Meier method and Cox semiparametric model. The median times to occurrence of severe oral mucositis were 35.3 and 77.1 days for patients with hematologic malignancies and solid tumors, respectively. The Cox model showed that white cell changes and platelet counts as well as the use of natural chemotherapeutic agents are risk factors for the occurrence of oral mucositis among patients with hematologic malignancies. Nonetheless, among patients with solid tumors, the occurrence of oral mucositis was associated with female sex, mixed ethnicity, the presence of metastasis, abnormal creatinine levels, a combination of chemotherapy, radiotherapy, and surgery, and the administration of chemotherapeutic agents included in the miscellaneous group. The time to occurrence of severe oral mucositis and its associated factors varied according to cancer type.
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