Evidence map›Paper›PMID 32075054›Full record

ArticleNutrients2020

Sanggenol L Induces Apoptosis and Cell Cycle Arrest via Activation of p53 and Suppression of PI3K/Akt/mTOR Signaling in Human Prostate Cancer Cells.

Yeong-Seon Won, Kwon-Il Seo

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.8field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
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  6. Article
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  8. Article
  9. Review
  10. Article
  11. Targeting PI3K/Akt signaling in prostate cancer therapy.Journal of cell communication and signaling · 2023
    Review
  12. Co-Delivery ofFrontiers in pharmacology · 2022
    Article
  13. Ailanthone Inhibits Cell Proliferation in Tongue Squamous Cell Carcinoma via PI3K/AKT Pathway.Evidence-based complementary and alternative medicine : eCAM · 2022
    Article
  14. Recent Advances in Phenolic Metabolites and Skin Cancer.International journal of molecular sciences · 2021
    Review
  15. Article
  16. Review
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Yeong-Seon WonDepartment of Biotechnology, Dong-A University, Busan 49315, Korea.
Kwon-Il SeoDepartment of Biotechnology, Dong-A University, Busan 49315, Korea.
Dong-A University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prostate cancer is the most common cancer in Western countries. Recently, Asian countries are being affected by Western habits, which have had an important role in the rapid increase in cancer incidence. Sanggenol L (San L) is a natural flavonoid present in the root barks of

Indexed as

ApoptosisCell Cycle CheckpointsCell Line, TumorFlavanonesHumansMaleMorusPhosphatidylinositol 3-KinasesPhytotherapyPlant RootsProstatic NeoplasmsProto-Oncogene Proteins c-aktSignal TransductionTOR Serine-Threonine KinasesTumor Suppressor Protein p53FlavanonesMTOR protein, humanPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktsanggenol LTOR Serine-Threonine KinasesTumor Suppressor Protein p53AIFapoptosisp53PI3K/Akt/mTORprostate cancersanggenol L

Identifiers

PMID32075054
PMCPMC7071324
OpenAlexW3006400706

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.