Evidence map›Paper›PMID 32074950›Full record

ArticleMicromachines2020

Lab-on-Chip Platform for Culturing and Dynamic Evaluation of Cells Development.

Agnieszka Podwin, Danylo Lizanets, Dawid Przystupski, Wojciech Kubicki, Patrycja Śniadek, Julita Kulbacka, Artur Wymysłowski, Rafał Walczak, Jan A Dziuban

Open access · goldAbstract read
In one paragraph

Article in Micromachines, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Agnieszka PodwinFaculty of Microsystem Electronics and Photonics, Wrocław University of Science and Technology, Wrocław 50-370, Poland.
Danylo LizanetsFaculty of Microsystem Electronics and Photonics, Wrocław University of Science and Technology, Wrocław 50-370, Poland.
Dawid PrzystupskiDepartment of Molecular and Cellular Biology, Faculty of Pharmacy, Wrocław Medical University, Wrocław 50-367, Poland.
Wojciech KubickiFaculty of Microsystem Electronics and Photonics, Wrocław University of Science and Technology, Wrocław 50-370, Poland.
Patrycja ŚniadekFaculty of Microsystem Electronics and Photonics, Wrocław University of Science and Technology, Wrocław 50-370, Poland.
Julita KulbackaDepartment of Molecular and Cellular Biology, Faculty of Pharmacy, Wrocław Medical University, Wrocław 50-367, Poland.
Artur WymysłowskiFaculty of Microsystem Electronics and Photonics, Wrocław University of Science and Technology, Wrocław 50-370, Poland.
Rafał WalczakFaculty of Microsystem Electronics and Photonics, Wrocław University of Science and Technology, Wrocław 50-370, Poland.
Jan A DziubanFaculty of Microsystem Electronics and Photonics, Wrocław University of Science and Technology, Wrocław 50-370, Poland.
Wrocław University of Science and Technology · PLWroclaw Medical University · PL

Funding

Narodowym Centrum Nauki 2015/19/BST8/01110Politechnika Wrocławska 049U/0039/19
6 · The paper itself

Abstract

This paper presents a full-featured microfluidic platform ensuring long-term culturing and behavioral analysis of the radically different biological micro-objects. The platform uses all-glass lab-chips and MEMS-based components providing dedicated micro-aquatic habitats for the cells, as well as their intentional disturbances on-chip. Specially developed software was implemented to characterize the micro-objects metrologically in terms of population growth and cells' size, shape, or migration activity. To date, the platform has been successfully applied for the culturing of freshwater microorganisms, fungi, cancer cells, and animal oocytes, showing their notable population growth, high mobility, and taxis mechanisms. For instance, circa 100% expansion of porcine oocytes cells, as well as nearly five-fold increase in

Indexed as

behavioral analysiscancer researchcell cultureIVM (In Vitro Maturation)lab-on-chip platformtaxis effects

Identifiers

PMID32074950
PMCPMC7074672
OpenAlexW3005548876

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.