Evidence map›Paper›PMID 32074366›Full record

ArticleMilitary medicine2020

Exposure to Intense Noise Causes Vestibular Loss.

Courtney E Stewart, Ariane C Kanicki, David S Bauer, Richard A Altschuler, W Michael King

Open access · bronzeAbstract read
In one paragraph

Article in Military medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Noise-Induced Hearing Loss.Journal of clinical medicine · 2023
    Review
  3. Article
  4. Subclinical Hearing Deficits in Noise-Exposed Firefighters.International journal of environmental research and public health · 2022
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Courtney E StewartKresge Hearing Research Institute, University of Michigan, 1150 W. Medical Center Drive, Ann Arbor, MI 48109-5616.
Ariane C KanickiKresge Hearing Research Institute, University of Michigan, 1150 W. Medical Center Drive, Ann Arbor, MI 48109-5616.
David S BauerKresge Hearing Research Institute, University of Michigan, 1150 W. Medical Center Drive, Ann Arbor, MI 48109-5616.
Richard A AltschulerKresge Hearing Research Institute, University of Michigan, 1150 W. Medical Center Drive, Ann Arbor, MI 48109-5616.
W Michael KingKresge Hearing Research Institute, University of Michigan, 1150 W. Medical Center Drive, Ann Arbor, MI 48109-5616.
University of Michigan–Ann Arbor · US

Funding

Sensory Mechanisms and Disorders - Administrative SupplementT32DC000011 · NIDCD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Michael Thomas Roberts · 1989 to 2026
$9.5M
Noise-Induced Synaptic Loss and Vestibular DysfunctionR01DC018003 · NIDCD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI KING, WILLIAM M · 2020 to 2023
$2.9M
Sound Evoked Eye and Head Movements Mediated by Vestibulo-Collic and Vestibulo-Ocular Reflex (VOR, VCR) Pathways: a Physiological Basis for Noise Induced Vestibular Loss (NIVL)R21DC015097 · NIDCD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI KING, WILLIAM M · 2016 to 2017
$418k
The Role of Irregular Vestibular Afferents in Spinal Motor ControlF32DC017063 · NIDCD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI STEWART, COURTNEY ELAINE · 2018 to 2018
$59k
NIDCD NIH HHS F32 DC017063NIDCD NIH HHS R01 DC018003NIDCD NIH HHS R21 DC015097NIDCD NIH HHS T32 DC000011
6 · The paper itself

Abstract

introductionThe vestibular system is essential for normal postural control and balance. Because of their proximity to the cochlea, the otolith organs are vulnerable to noise. We previously showed that head jerks that evoke vestibular nerve activity were no longer capable of inducing a response after noise overstimulation. The present study adds a greater range of jerk intensities to determine if the response was abolished or required more intense stimulation (threshold shift). MATERIALS AND

methodsVestibular short-latency evoked potential (VsEP) measurements were taken before noise exposure and compared to repeated measurements taken at specific time points for 28 days after noise exposure. Calretinin was used to identify changes in calyx-only afferents in the sacculus.

resultsResults showed that more intense jerk stimuli could generate a VsEP, although it was severely attenuated relative to prenoise values. When the VsEP was evaluated 4 weeks after noise exposure, partial recovery was observed.

conclusionThese data suggest that noise overstimulation, such as can occur in the military, could introduce an increased risk of imbalance that should be evaluated before returning a subject to situations that require normal agility and motion. Moreover, although there is recovery with time, some dysfunction persists for extended periods.

Indexed as

AnimalsBilateral VestibulopathyDisease Models, AnimalEnvironmental ExposureEvoked Potentials, AuditoryEvoked Potentials, Auditory, Brain StemNoiseRats, Inbred LEC

Identifiers

PMID32074366
PMCPMC7029773
OpenAlexW3008124435

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.