Evidence map›Paper›PMID 32074033›Full record

ArticleJournal of medical imaging and radiation sciences2018

Clinical Implementation of Magnetic Resonance Imaging Systems for Simulation and Planning of Pediatric Radiation Therapy.

Chia-Ho Hua, Jinsoo Uh, Matthew J Krasin, John T Lucas, Christopher L Tinkle, Sahaja Acharya, Hanna L Smith, Mo Kadbi, Thomas E Merchant

Open access · greenAbstract read
In one paragraph

Article in Journal of medical imaging and radiation sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Chia-Ho HuaDepartment of Radiation Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA. Electronic address: chia-ho.hua@stjude.org.
Jinsoo UhDepartment of Radiation Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Matthew J KrasinDepartment of Radiation Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
John T LucasDepartment of Radiation Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Christopher L TinkleDepartment of Radiation Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Sahaja AcharyaDepartment of Radiation Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Hanna L SmithDepartment of Radiation Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Mo KadbiPhilips Healthcare, Highland Heights, Ohio, USA.
Thomas E MerchantDepartment of Radiation Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
St. Jude Children's Research Hospital · USHighland Community College - Illinois · US

Funding

Viral Vector Technology (VVTSR)P30CA021765 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI CHARLES ROBERTS · 1985 to 2026
$166.9M
NCI NIH HHS P30 CA021765
6 · The paper itself

Abstract

aimTo describe the clinical implementation and optimization of magnetic resonance imaging (MRI) systems installed in a radiation oncology department for dedicated use in radiotherapy (RT) simulation and treatment planning for pediatric patients.

methodsTwo wide-bore MRI systems were installed and commissioned in 2016. Patient setups, coil placements, and scan protocols were developed to image various anatomic sites in children. Patients with brain tumors were routinely imaged using a pair of flexible loop coils and a posterior receiver coil integrated into the patient couch. The integrated posterior coil and the flexible anterior torso coil supported by the coil bridge were used together when imaging the abdomen, pelvis, or spine. A three-dimensional acquisition was most often performed, given the benefit of high-resolution multiplanar reformation as well as elimination of B0-related distortions in the slice selection direction.

resultsWe performed 542 MRI studies (265 for planning and 277 for monitoring on-treatment tumor changes) on pediatric patients in the first year after system installation. Multisequence images of pediatric RT patients with ependymoma, medulloblastoma, craniopharyngioma, rhabdomyosarcoma, or Ewing sarcoma were shown to illustrate the image quality obtainable with optimized planning sequences.

conclusionsMagnetic resonance imaging (MRI) of pediatric patients in their treatment positions with setup devices in place can be performed with coil arrangements that include flexible coils. The resulting image quality is suitable for treatment planning and on-treatment monitoring. We provide optimized site-specific sequence parameters to support the continued improvement of MRI for pediatric RT planning.

Identifiers

PMID32074033
PMCPMC8802339
OpenAlexW2795354402

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.