Evidence map›Paper›PMID 32073901›Full record

ArticleAmerican journal of physiology. Lung cellular and molecular physiology2020

Nitrite attenuates mitochondrial impairment and vascular permeability induced by ischemia-reperfusion injury in the lung.

Ajay Kumar, Kentaro Noda, Brian Philips, Murugesan Velayutham, Donna B Stolz, Mark T Gladwin, Sruti Shiva, Jonathan D'Cunha

Open access · greenAbstract read
In one paragraph

Article in American journal of physiology. Lung cellular and molecular physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Ajay KumarDivision of Lung Transplantation and Lung Failure, Department of Cardiothoracic Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania.
Kentaro NodaDivision of Lung Transplantation and Lung Failure, Department of Cardiothoracic Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania.ORCID 0000-0001-8921-1944
Brian PhilipsDivision of Lung Transplantation and Lung Failure, Department of Cardiothoracic Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania.
Murugesan VelayuthamVascular Medicine Institute, University of Pittsburgh, Pittsburgh, Pennsylvania.
Donna B StolzCenter for Biological Imaging, University of Pittsburgh, Pittsburgh, Pennsylvania.
Mark T GladwinVascular Medicine Institute, University of Pittsburgh, Pittsburgh, Pennsylvania.
Sruti ShivaVascular Medicine Institute, University of Pittsburgh, Pittsburgh, Pennsylvania.
Jonathan D'CunhaDepartment of Cardiothoracic Surgery, Mayo Clinic Arizona, Phoenix, Arizona.
University of Pittsburgh · USMayo Clinic Hospital · US

Funding

Storage Lesion in Banked Blood Due to Disruption of Nitric Oxide HomeostasisR01HL098032 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Mark T Gladwin · 2009 to 2026
$12.5M
Antidote for inhaled CO poisoning based on mutationally engineered neuroglobinR01HL125886 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Mark T Gladwin, Jesus Tejero Bravo · 2015 to 2026
$7.9M
Translational Pulmonary Vascular BiologyT32HL110849 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Sruti Shiva · 2012 to 2026
$5.0M
NHLBI NIH HHS R01 HL098032NHLBI NIH HHS R01 HL125886NHLBI NIH HHS T32 HL110849
6 · The paper itself

Abstract

Primary graft dysfunction (PGD) is directly related to ischemia-reperfusion (I/R) injury and a major obstacle in lung transplantation (LTx). Nitrite (

Indexed as

A549 CellsAnimalsCapillary PermeabilityCell Line, TumorCytoprotectionElectron Transport Complex IEndothelial CellsHumansHypoxiaLungLung TransplantationMaleMembrane Potential, MitochondrialMiceMice, Inbred C57BLMitochondriaElectron Transport Complex INitritesReactive Oxygen Speciesendothelial barrier functionischemia-reperfusion injurylung transplantationmitochondrial dysfunctionnitriteprimary graft dysfunctionvascular permeability

Identifiers

PMID32073901
PMCPMC7191477
OpenAlexW3007262398

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.