ArticleEnvironmental science & technology2020
Evaluating the Environmental Persistence and Inactivation of MS2 Bacteriophage and the Presumed Ebola Virus Surrogate Phi6 Using Low Concentration Hydrogen Peroxide Vapor.
Article in Environmental science & technology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A Systematic Review on the Efficacy of Vaporized Hydrogen Peroxide as a Non-Contact Decontamination System for Pathogens Associated with the Dental Environment.International journal of environmental research and public health · 2021Pooled it
- Doffing procedures of personal protective equipment evaluated with lipid nanoparticles as viral surrogates: uncovering potential blind spots.Antimicrobial resistance and infection control · 2025Article
- Aerosolic Application of Phages AgainstPHAGE (New Rochelle, N.Y.) · 2024Article
- RNA and Single-Stranded DNA Phages: Unveiling the Promise from the Underexplored World of Viruses.International journal of molecular sciences · 2023Review
- Review
- Disinfection of Phi6, MS2, and Escherichia coli by Natural Sunlight on Healthcare Critical Surfaces.The American journal of tropical medicine and hygiene · 2023Article
- Surface Inactivation of a SARS-CoV-2 Surrogate with Hypochlorous Acid is Impacted by Surface Type, Contact Time, Inoculum Matrix, and Concentration.Food and environmental virology · 2023Article
- Antiviral activity of nano-monocaprin against Phi6 as a surrogate for SARS-CoV-2.International microbiology : the official journal of the Spanish Society for Microbiology · 2023Article
- Passenger vehicle interior decontamination by low concentration hydrogen peroxide vapor following a wide area biological contamination incident.Journal of applied microbiology · 2023Article
- Prophylaxis and Remediation for Future Pandemic Pathogens-(Lessons from a Post-COVID World).Microorganisms · 2022Article
- Enhancing the Stability of Bacteriophages Using Physical, Chemical, and Nano-Based Approaches: A Review.Pharmaceutics · 2022Review
- Analysis of the anaerobic digestion metagenome under environmental stresses stimulating prophage induction.Microbiome · 2022Article
- Factors Impacting Persistence of Phi6 Bacteriophage, an Enveloped Virus Surrogate, on Fomite Surfaces.Applied and environmental microbiology · 2022Article
- Hydrogen Peroxide Vapor Decontamination of Hazard Group 3 Bacteria and Viruses in a Biosafety Level 3 Laboratory.Applied biosafety : journal of the American Biological Safety Association · 2022Article
- Clinical and experimental bacteriophage studies: Recommendations for possible approaches for standing against SARS-CoV-2.Microbial pathogenesis · 2022Review
- Phi 6 recovery from inoculated fingerpads based on elution buffer and methodology.Journal of virological methods · 2022Article
- Validation of the Decontamination of a Specialist Transport System for Patients with High Consequence Infectious Diseases.Microorganisms · 2021Article
- Ultra-fast and onsite interrogation of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in waters via surface enhanced Raman scattering (SERS).Water research · 2021Article
- Scalable in-hospital decontamination of N95 filtering face-piece respirator with a peracetic acid room disinfection system.Infection control and hospital epidemiology · 2021Article
- Bacteriophage Capsid Modification by Genetic and Chemical Methods.Bioconjugate chemistry · 2021Review
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Ebola virus (EBOV) disease outbreaks, as well as the ability of EBOV to persist in the environment under certain conditions, highlight the need to develop effective decontamination techniques against the virus. We evaluated the efficacy of hydrogen peroxide vapor (HPV) to inactivate MS2 and Phi6 bacteriophages, the latter a recommended surrogate for EBOV. The phages were inoculated onto six material types with and without the presence of whole human blood. The inoculated materials were then exposed to either a high or low concentration of HPV for various elapsed times. The phages were also recovered from positive controls at these same elapsed times, to assess environmental persistence and decontamination efficacy. Low concentration hydrogen peroxide vapor (LCHP; 25 ppm) was effective against both phages on all materials without the presence of blood at 2 h. LCHP was ineffective against the phages in the presence of blood, on all materials, even with a 3-day contact time. Higher concentrations of HPV (>400 ppm) with contact times of 24-32 h achieved approximately 2-6 log reduction of the phages in the presence of blood.
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Registered trials
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