Evidence map›Paper›PMID 32073444›Full record

ArticleAIDS (London, England)2020

Material security and adherence to antiretroviral therapy among HIV-positive people who use illicit drugs.

Nur Afiqah Mohd Salleh, Jenna Van Draanen, Ekaterina Nosova, Rolando Barrios, M-J Milloy, Lindsey Richardson

Abstract read
In one paragraph

Article in AIDS (London, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nur Afiqah Mohd SallehInterdisciplinary Studies Graduate Program, University of British Columbia.
Jenna Van DraanenBritish Columbia Centre on Substance Use, Vancouver, British Columbia, Canada.
Ekaterina NosovaBritish Columbia Centre on Substance Use, Vancouver, British Columbia, Canada.
Rolando BarriosBC Centre for Excellence in HIV/AIDS, St. Paul's Hospital.
M-J MilloyBritish Columbia Centre on Substance Use, Vancouver, British Columbia, Canada.
Lindsey RichardsonBritish Columbia Centre on Substance Use, Vancouver, British Columbia, Canada.

Funding

Impacts of universal access to HIV/AIDS care among HIV+ injection drug usersU01DA021525 · NIDA · UNIVERSITY OF BRITISH COLUMBIA · PI MILLOY, M-J · 2017 to 2024
$4.3M
NIDA NIH HHS U01 DA021525
6 · The paper itself

Abstract

objectiveTo examine the relationship between poverty, operationalized using a novel material security measure, and adherence to antiretroviral therapy (ART) among people who use illicit drugs (PWUD) in a context of universal access to HIV care.

designWe analyzed data from a community-recruited prospective cohort in Vancouver, Canada (n = 623), from 2014 to 2017.

methodsWe used multivariable generalized mixed-effects analyses to estimate longitudinal factors associated with mean material security score. We then estimated the association between achieving at least 95% adherence to ART and overall mean material score, as well as mean score for three factors derived from a factor analysis. The three-factor structure, employed in the current analyses, were factor 1 (basic needs); factor 2 (housing-related variables) and factor 3 (economic resources).

resultsRecent incarceration [β-coefficient (β) = -0.176, 95% confidence interval (95% CI): -0.288 to -0.063], unmet health needs [β = -0.110, 95% CI: -0.178 to -0.042), unmet social service needs (β = -0.264, 95% CI: -0.336 to -0.193) and having access to social services (β= -0.102, 95% CI: -0.1586 to -0.0465) were among the factors associated with lower material security scores. Contrary to expectations that low levels of material security in this population would lead to poor ART adherence, we did not observe a significant relationship between adherence and overall material security score, or for each factor individually.

conclusionOur findings highlight the potentially important role of no-cost, universal access to HIV prevention and treatment, in mitigating the impact of socioeconomic disadvantage on ART adherence.

Indexed as

AdultAnti-HIV AgentsAntiretroviral Therapy, Highly ActiveCanadaDrug UsersHIV InfectionsHumansIllicit DrugsMaleMedication AdherenceMiddle AgedProspective StudiesSocial MarginalizationSubstance-Related DisordersAnti-HIV AgentsIllicit Drugs

Identifiers

PMID32073444
PMCPMC7210079

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.