Evidence map›Paper›PMID 32072817›Full record

ArticleClinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis

Relationship Between 25-Hydroxyvitamin D, Renin, and Collagen Remodeling Biomarkers in Atrial Fibrillation.

Dimpi Patel, Aleksander Druck, Debra Hoppensteadt, Vinod Bansal, Yevgeniy Brailovsky, Mushabbar Syed, Jawed Fareed

Open access · goldAbstract read
In one paragraph

Article in Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. 1α,25(OH)Bioengineered · 2022
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Dimpi PatelLoyola University of Chicago, Stritch School of Medicine, Maywood, IL, USA.ORCID https://orcid.org/0000-0003-4378-3589
Aleksander DruckLoyola University of Chicago, Stritch School of Medicine, Maywood, IL, USA.ORCID https://orcid.org/0000-0002-3090-7960
Debra HoppensteadtHemostasis and Thrombosis Laboratories, Center of Translational Research and Education, Maywood, IL, USA.
Vinod BansalLoyola University Medical Center, Maywood, IL, USA.
Yevgeniy BrailovskyCenter for Advanced Cardiac Care, Columbia University Medical Center, New York, NY, USA.ORCID https://orcid.org/0000-0002-4811-5267
Mushabbar SyedLoyola University Medical Center, Maywood, IL, USA.
Jawed FareedHemostasis and Thrombosis Laboratories, Center of Translational Research and Education, Maywood, IL, USA.ORCID https://orcid.org/0000-0003-3465-2499
Loyola University Chicago · USLoyola University Medical Center · USColumbia University Irving Medical Center · US

Funding

Basic and Clinical Research Training for Medical StudentsT35HL120835 · NHLBI · LOYOLA UNIVERSITY CHICAGO · PI ZELEZNIK-LE, NANCY J · 2015 to 2024
$628k
Summer Research Experience for Medical Students in Inflammation and Infectious DiseasesT35AI125220 · NIAID · LOYOLA UNIVERSITY CHICAGO · PI Edward M. Campbell, Simon Kaja · 2017 to 2026
$510k
NHLBI NIH HHS T35 HL120835NIAID NIH HHS T35 AI125220
6 · The paper itself

Abstract

The interplay between vitamin D, the renin-angiotensin system (RAS), and collagen remodeling has been implicated in the pathogenesis of various cardiovascular diseases. This study sought to explore this relationship in atrial fibrillation (AF) by profiling plasma levels of 25-hydroxyvitamin D, RAS biomarkers, and collagen remodeling biomarkers using the enzyme-linked immunosorbent assay method. We hypothesized that 25-hydroxyvitamin D levels would inversely correlate with RAS biomarkers and that levels of RAS and collagen remodeling biomarkers would positively correlate with each other. Although our AF cohort (n = 37) did not exhibit decreased 25-hydroxyvitamin D levels compared to normal controls (n = 26), these levels inversely correlated with renin (Spearman

Indexed as

AdultAgedAtrial FibrillationBiomarkersCase-Control StudiesCollagenFemaleHumansMaleMiddle AgedReninVitamin D25-hydroxyvitamin DBiomarkersCollagenReninVitamin Datrial fibrillationcollagen remodelingrenin–angiotensin systemvitamin D

Identifiers

PMID32072817
PMCPMC7288844
OpenAlexW3007651913

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.