Evidence map›Paper›PMID 32072802›Full record

ArticleJBRA assisted reproduction2020

The effect of fresh IVF cycle characteristics on frozen embryo transfer (FET) outcomes.

Nayla J Bushaqer, Noor N Alkhudhairy, Ziyad M Alturaigi, Rowaida M Alhamad, Wadha A Mohawesh, Fatema E Alraka, Hisham A Ayyoub, M Dayou Nawal

Open access · bronzeAbstract read
In one paragraph

Article in JBRA assisted reproduction, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Nayla J BushaqerSaudi Board of OB/GYN.
Noor N AlkhudhairyIVF unit, Prince Sultan Military Medical City (PSMMC), Riyadh, KSA.
Ziyad M AlturaigiIVF unit, Prince Sultan Military Medical City (PSMMC), Riyadh, KSA.
Rowaida M AlhamadIVF unit, Prince Sultan Military Medical City (PSMMC), Riyadh, KSA.
Wadha A MohaweshSaudi Board of OB/GYN.
Fatema E AlrakaSaudi Board of OB/GYN.
Hisham A AyyoubPrince Sultan Military Medical City, Riyadh, KSA.
M Dayou NawalBahrain Defense Force (BDF) Hospital, Riffa, Bahrain.
Riyadh Armed Forces Hospital · SABahrain Center for Strategic International and Energy Studies · BHKing Fahd Military Medical Complex · SAKing Saud Medical City · SARoyal College of Surgeons in Ireland - Bahrain · BH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine the effect of fresh IVF/ICSI cycles on FET cycle embryo and pregnancy outcomes.

methodsThis retrospective cohort study included data from the medical records of 104 FET cycles performed from January 2014 to December 2016. Embryos were previously vitrified and then thawed for embryo transfer. Statistical significance was established at p<0.05. The main endpoints were FET cycle survival and pregnancy rates.

resultsA total of 104 FET cycles were analyzed for survival; 94 showed good progression and 84 achieved embryo transfers. Patients with secondary infertility achieved significantly higher pregnancy rates - 6/38 (15.8%) vs. 18/46 (39.1%) (p<0.018). Stimulation with FSH/LH resulted in more significant embryo progression, 38/48 (79.2%) vs. 28/46 (60.9%) in the FSH group (p=0.01). Patients who got pregnant from fresh cycles had the highest pregnancy rates in FET cycles (p<0.0001). Lower numbers of frozen embryos correlated with higher pregnancy rates (p=0.048). Embryos frozen on day 2 or 3 had the most significant progression (p<0.0001). Freeze-thaw intervals >12 months yielded higher pregnancy rates, 13/30 (43%), vs. 11/54 (20.4%) (p=0.025).

conclusionPatient pregnancy in fresh cycles is a good prognostic factor for FET cycle success. Delaying FET by more than 12 months might result in higher pregnancy rates.

Indexed as

Embryo TransferFertilization in VitroAdultCryopreservationFemaleHumansInfertility, FemalePregnancyPregnancy OutcomeRetrospective StudiesSperm Injections, Intracytoplasmiccryopreservationfrozen embryo transfer (FET)Intra-Cytoplasmic Sperm Injection (ICSI)in vitro fertilization (IVF)thawing

Identifiers

PMID32072802
PMCPMC7169927
OpenAlexW3011242878

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.