ArticleAdvanced materials (Deerfield Beach, Fla.)2020
Thermal-Disrupting Interface Mitigates Intercellular Cohesion Loss for Accurate Topical Antibacterial Therapy.
Article in Advanced materials (Deerfield Beach, Fla.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 113 citations in OpenAlex.
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- Skin-mimetic bilayer hydrogel enhances spatiotemporal coordination of neuro-immune-vascular interactions to accelerate diabetic wound healing.Bioactive materials · 2026Article
- Biomimetic Dynamics of Nanoscale Groove and Ridge Topography for Stem Cell Regulation.Advanced materials (Deerfield Beach, Fla.) · 2025Article
- Emerging synergistic strategies for enhanced antibacterial sonodynamic therapy: Advances and prospects.Ultrasonics sonochemistry · 2025Review
- Intratumoral self-assembly of renal-clearable gold nanoparticles as precise photothermal nanomedicine for liver tumor therapy.Science advances · 2025Article
- Fast fabrication of "all-in-one" injectable hydrogels as antibiotic alternatives for enhanced bacterial inhibition and accelerating wound healing.Journal of nanobiotechnology · 2024Article
- Nanomaterials for Photothermal Antimicrobial Surfaces.ACS omega · 2024Review
- Metal nanoparticle hybrid hydrogels: the state-of-the-art of combining hard and soft materials to promote wound healing.Theranostics · 2024Review
- Fluoride-activated photothermal system for promoting bacteria-infected wound healing.Journal of nanobiotechnology · 2023Article
- Progress of Hydrogel Dressings with Wound Monitoring and Treatment Functions.Gels (Basel, Switzerland) · 2023Review
- Emerging nanosonosensitizers augment sonodynamic-mediated antimicrobial therapies.Materials today. Bio · 2023Review
- Photonics-based treatments: Mechanisms and applications in oral infectious diseases.Frontiers in microbiology · 2023Review
- Recent Progress on Bioinspired Antibacterial Surfaces for Biomedical Application.Biomimetics (Basel, Switzerland) · 2022Review
- Cyanobacteria-based self-oxygenated photodynamic therapy for anaerobic infection treatment and tissue repair.Bioactive materials · 2022Article
- Recent Research on Hybrid Hydrogels for Infection Treatment and Bone Repair.Gels (Basel, Switzerland) · 2022Review
- Antibacterial biomaterials for skin wound dressing.Asian journal of pharmaceutical sciences · 2022Review
- Transparent photothermal hydrogels for wound visualization and accelerated healing.Fundamental research · 2022Article
- Accelerated antibacterial red-carbon dots with photodynamic therapy against multidrug-resistantScience China materials · 2022Article
- Surface Design for Antibacterial Materials: From Fundamentals to Advanced Strategies.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021Review
- Triggering Drug Release and Thermal-Disrupting Interface Induced Mitigation of Composite Photothermal Hydrogel Treating Infectious Wounds.Frontiers in bioengineering and biotechnology · 2021Article
Corrections and comments
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Authors and funding
22 authors at 5 institutions in 3 countries.
Funding
Abstract
Bacterial infections remain a leading threat to global health because of the misuse of antibiotics and the rise in drug-resistant pathogens. Although several strategies such as photothermal therapy and magneto-thermal therapy can suppress bacterial infections, excessive heat often damages host cells and lengthens the healing time. Here, a localized thermal managing strategy, thermal-disrupting interface induced mitigation (TRIM), is reported, to minimize intercellular cohesion loss for accurate antibacterial therapy. The TRIM dressing film is composed of alternative microscale arrangement of heat-responsive hydrogel regions and mechanical support regions, which enables the surface microtopography to have a significant effect on disrupting bacterial colonization upon infrared irradiation. The regulation of the interfacial contact to the attached skin confines the produced heat and minimizes the risk of skin damage during thermoablation. Quantitative mechanobiology studies demonstrate the TRIM dressing film with a critical dimension for surface features plays a critical role in maintaining intercellular cohesion of the epidermis during photothermal therapy. Finally, endowing wound dressing with the TRIM effect via in vivo studies in S. aureus infected mice demonstrates a promising strategy for mitigating the side effects of photothermal therapy against a wide spectrum of bacterial infections, promoting future biointerface design for antibacterial therapy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.