Evidence map›Paper›PMID 32072661›Full record

ArticleBioelectromagnetics2020

The Effects of Mobile Phone Radiofrequency Radiation on Cochlear Stria Marginal Cells in Sprague-Dawley Rats.

Honghong Yang, Yuanyuan Zhang, Zhihai Wang, Shixun Zhong, Guohua Hu, Wenqi Zuo

Open access · hybridAbstract read
In one paragraph

Article in Bioelectromagnetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Honghong YangDepartment of Otorhinolaryngology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Yuanyuan ZhangDepartment of Otolaryngology Head and Neck Surgery, Renmin Hospital of Wuhan University, Wuhan, China.
Zhihai WangDepartment of Otorhinolaryngology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Shixun ZhongDepartment of Otorhinolaryngology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Guohua HuDepartment of Otorhinolaryngology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Wenqi ZuoDepartment of Otorhinolaryngology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.ORCID http://orcid.org/0000-0002-1109-3500
The Affiliated Yongchuan Hospital of Chongqing Medical University · CNWuhan University · CN

Funding

Chongqing Science and Technology Commission 20180105Chongqing Science and Technology Commission KJQN201900433National Natural Science Foundation of China 81700916
6 · The paper itself

Abstract

To investigate the possible mechanisms for biological effects of 1,800 MHz mobile radiofrequency radiation (RFR), the radiation-specific absorption rate was applied at 2 and 4 W/kg, and the exposure mode was 5 min on and 10 min off (conversation mode). Exposure time was 24 h short-term exposure. Following exposure, to detect cell DNA damage, cell apoptosis, and reactive oxygen species (ROS) generation, the Comet assay test, flow cytometry, DAPI (4',6-diamidino-2-phenylindole dihydrochloride) staining, and a fluorescent probe were used, respectively. Our experiments revealed that mobile phone RFR did not cause DNA damage in marginal cells, and the rate of cell apoptosis did not increase (P > 0.05). However, the production of ROS in the 4 W/kg exposure group was greater than that in the control group (P < 0.05). In conclusion, these results suggest that mobile phone energy was insufficient to cause cell DNA damage and cell apoptosis following short-term exposure, but the cumulative effect of mobile phone radiation still requires further confirmation. Activation of the ROS system plays a significant role in the biological effects of RFR. Bioelectromagnetics. © 2020 The Authors. Bioelectromagnetics published by Wiley Periodicals, Inc.

Indexed as

Cell PhoneAnimalsApoptosisCells, CulturedDNA DamageFemaleMaleRadio WavesRats, Sprague-DawleyReactive Oxygen SpeciesStria VascularisReactive Oxygen Speciescell apoptosiscochlear stria marginal cellsDNA damageradiofrequency radiationreactive oxygen species

Identifiers

PMID32072661
PMCPMC7154754
OpenAlexW3008004479

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.