Evidence map›Paper›PMID 32072434›Full record

Trial reportJournal of cancer survivorship : research and practice2020

Effects of dietary and physical activity interventions on generic and cancer-specific health-related quality of life, anxiety, and depression in colorectal cancer survivors: a randomized controlled trial.

Mandy Ho, Judy W C Ho, Daniel Y T Fong, C F Lee, Duncan J Macfarlane, Ester Cerin, Antoinette M Lee, Sharron Leung, Wynnie Y Y Chan, Ivy P F Leung and 4 more

Registry-linked trialOpen access · hybridAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of cancer survivorship : research and practice, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01708824 (The Acceptability and Feasibility of a Diet and Physical Activity Intervention to Prevent Recurrence in Colorectal Cancer Survivors), which is not on this map. Cited by 74 papers, 16 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
74citing papers in PubMed, 16 pooled it
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01708824 phase2unknown statusnot on this map

The Acceptability and Feasibility of a Diet and Physical Activity Intervention to Prevent Recurrence in Colorectal Cancer Survivors: a Phase 2 Study

TypeinterventionalSponsorThe University of Hong KongRan2013 to 2017Enrolled224ConditionsColorectal CancerArmsDietary, Physical activity
3 · Its place in the literature

Who cites it

74 citing papers in PubMed, 16 syntheses or guidelines pooled it, 108 citations in OpenAlex.

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  8. Effects of internet-based digital health interventions on the physical activity and quality of life of colorectal cancer survivors: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
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14 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 4 countries.

Mandy HoSchool of Nursing, The University of Hong Kong, 4/F William M.W. Mong Block, 21 Sassoon Road, Pok Fu Lam, Hong Kong.
Judy W C HoDepartment of Surgery, The University of Hong Kong, Pok Fu Lam, Hong Kong.
Daniel Y T FongSchool of Nursing, The University of Hong Kong, 4/F William M.W. Mong Block, 21 Sassoon Road, Pok Fu Lam, Hong Kong. dytfong@hku.hk.
C F LeeCentre for Sports and Exercise, The University of Hong Kong, Pok Fu Lam, Hong Kong.
Duncan J MacfarlaneCentre for Sports and Exercise, The University of Hong Kong, Pok Fu Lam, Hong Kong.
Ester CerinSchool of Public Health, The University of Hong Kong, Pok Fu Lam, Hong Kong.
Antoinette M LeeDepartment of Psychology, The University of Hong Kong, Pok Fu Lam, Hong Kong.
Sharron LeungSchool of Nursing, Hong Kong Baptist Hospital, Kowloon Tong, Hong Kong.
Wynnie Y Y ChanSchool of Professional and Continuing Education, The University of Hong Kong, Pok Fu Lam, Hong Kong.
Ivy P F LeungDepartment of Dietetics, Queen Elizabeth Hospital, Kowloon, Hong Kong.
Sharon H S LamCentre for Sports and Exercise, The University of Hong Kong, Pok Fu Lam, Hong Kong.
Natural ChuDepartment of Surgery, The University of Hong Kong, Pok Fu Lam, Hong Kong.
Aliki J TaylorInstitute of Applied Health Research, University of Birmingham, Birmingham, UK.
Kar-Keung ChengInstitute of Applied Health Research, University of Birmingham, Birmingham, UK.
University of Hong Kong · HKUniversity of Birmingham · GBAustralian Catholic University · AUHong Kong Baptist Hospital · HKQueen Elizabeth Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo assess the effects of dietary and physical activity (PA) interventions on generic and cancer-specific quality of life (QoL), anxiety, and depression levels among adult Chinese colorectal cancer (CRC) survivors.

methodsTwo-hundred twenty-three adult CRC survivors within 1 year of completion of primary cancer treatment were randomized to receive dietary, PA or combined intervention, or usual care for a 12 monthduration, under a 2 (diet vs usual care) × 2 (PA vs usual care) factorial design. Generic and cancer-specific QoL was assessed using a Chinese version 12-Item Short Form Health Survey (SF-12) and the Functional Assessment of Cancer Therapy-Colorectal (FACT-C) scale, respectively. Anxiety and depression was assessed using the Hospital Anxiety and Depression Scale at baseline, 6, 12, 18, and 24 months. Linear mixed models were used for examining the intervention effects.

resultsParticipants receiving dietary intervention experienced a significant improvement in the generic measure of QoL (SF-6D utility scores, mean difference 0.042, 95%CI 0.03 to 0.081) at 12 months, the cancer-specific QoL scores (mean difference 3.09, 95%CI 0.13 to 6.04), and levels of depression (P = 0.015) at both 12 and 24 months follow-up. Participants receiving PA intervention only demonstrated a significant improvement in SF-6D utility index (mean difference 0.039, 95%CI 0.002 to 0.077) and physical functioning (mean difference 2.85, 95%CI 1.00 to 4.70) at 6 months.

conclusionsDietary intervention improved the generic and cancer-specific QoL and depression in CRC survivors.

trial registrationThe study was prospectively registered on 17 October 2012 at ClinicalTrials.gov (NCT01708824). IMPLICATIONS FOR CANCER SURVIVORS: CRC survivors can benefit from dietary interventions in alleviating depression and improving overall health-related QoL.

Indexed as

AdultAgedAged, 80 and overAnxietyCancer SurvivorsColorectal NeoplasmsDepressionDietExerciseFemaleHumansMaleMiddle AgedQuality of LifeSurvivorsAnxietyCancer survivorshipColorectal cancerDepressionDietary interventionHealth-related quality of lifePhysical activity intervention

Identifiers

PMID32072434
PMCPMC7360640
OpenAlexW3007849832

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.