Evidence map›Paper›PMID 32072429›Full record

ArticleDiabetes therapy : research, treatment and education of diabetes and related disorders2020

Development and Validation of a New Diabetes Risk Score in Guyana.

Julia Lowe, Calvin Ke, Kavita Singh, Reeta Gobin, Gerald Lebovic, Brian Ostrow

Abstract read
In one paragraph

Article in Diabetes therapy : research, treatment and education of diabetes and related disorders, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Julia LoweDivision of Endocrinology and Metabolism, Department of Medicine, University of Toronto, Toronto, Canada. Julia.Lowe@newcastle.edu.au.ORCID http://orcid.org/0000-0002-7162-6057
Calvin KeDivision of Endocrinology and Metabolism, Department of Medicine, University of Toronto, Toronto, Canada.
Kavita SinghChronic Diseases Unit, Ministry of Public Health, Lot 1 Brickdam St., Georgetown, Guyana.
Reeta GobinMaster of Public Health Programme, University of Guyana, Turkeyan Campus, Georgetown, Guyana.
Gerald LebovicApplied Health Research Centre, St. Michael's Hospital, Toronto, Canada.
Brian OstrowDepartment of Surgery, University of Toronto, Toronto, Canada.

Funding

Banting and Best Diabetes Centre, University of Toronto 14-862Banting and Best Diabetes Centre, University of Toronto 499334Medical Research Council MR/N015959/1Medical Research Council MR/R022739/1WDF 14-862
6 · The paper itself

Abstract

introductionWe present a new diabetes risk score developed and validated in a multi-ethnic population in Guyana, South America. Measurement of in-country diabetes prevalence is a vital epidemiologic tool to combat the pandemic. It is believed that for every person diagnosed with type 2 diabetes there is another undiagnosed. The International Diabetes Federation (IDF) recommends a two-step detection programme using a risk score questionnaire to identify high-risk individuals followed by glycaemic measure.

methodsData on 798 persons from the 2016 STEPwise Approach to Chronic Disease Risk Factor Surveillance (STEPS) were used to correlate responses to 36 questions with glycated haemoglobin (HbA1C) and fasting plasma glucose (FPG) results. Bootstrapping was used to internally validate the derived seven-variable model. This model with the addition of family history questions was tested in a convenience sample of 659 Guyanese adults and externally validated in a cohort of another 528.

resultsAn 8-item Guyana Diabetes Risk Score (GDRS) was derived. The final model performed with an area under the curve (AUC) of 0.812

conclusionsThe validated eight-item Guyana Diabetes Risk Score will be extremely useful in identifying individuals at high risk of having diabetes in Caribbean, Black or East Indian populations.

Indexed as

Community screeningDiabetes mellitusRisk scoreSensitivity and specificityValidation

Identifiers

PMID32072429
PMCPMC7136361

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.