ArticleJournal of behavioral medicine2020
Social support moderates D-dimer and self-rated successful aging within people with HIV and older adults.
Article in Journal of behavioral medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.
- Health Outcomes Associated with Loneliness and Social Isolation in Older Adults Living with HIV: A Systematic Review.AIDS and behavior · 2025Pooled it
- Relationship between self-perceptions of ageing and interoception among older people living with HIV: a latent profile analysis.BMC public health · 2026Article
- Analysis of risk factors of social frailty in older adults living with HIV/AIDS.Scientific reports · 2025Article
- Successful Aging is Associated with Better Health Literacy in Older Adults with HIV Disease.AIDS and behavior · 2024Article
- The impact of social support for older adults in nursing homes on successful aging: a moderated mediation model.Frontiers in public health · 2024Article
- Preference for care models among older people living with HIV: cross-sectional study.BMC public health · 2023Article
- Combined effects of loneliness and inflammation on depression in people with HIV.Journal of neurovirology · 2023Article
- Felt Age Discrepancy Differs by HIV Serostatus: A Secondary Analysis.The Journal of the Association of Nurses in AIDS Care : JANACArticle
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
Abstract
Many factors can influence perceptions of successful aging (SA), including social isolation and poor physical health. We hypothesized that social support attenuates the negative effect of plasma D-dimer, a correlate of HIV and aging, on SA. Participants included 230 adults (134 people with HIV; PWH, 96 HIV-), ages 36-65, segregated into age cohorts with up to 5 yearly visits. Multilevel modeling examined longitudinal within-person associations between D-dimer, social support, and SA. Social support moderated the relationship between D-dimer and SA and was significant among PWH and older individuals (ages 56-65), but not HIV- or younger cohorts. This association was significant only at extreme levels of social support, with significant decreases in social support potentiating the negative impact of D-dimer on SA and significant increases in social support facilitating increased SA. Despite declining health, high social support may improve SA in PWH and older adults, and low support may be especially problematic for older adults.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.