Evidence map›Paper›PMID 32072288›Full record

ArticleSurgical endoscopy2021

Extended right colectomy, left colectomy, or segmental left colectomy for splenic flexure carcinomas: a European multicenter propensity score matching analysis.

Nicola de'Angelis, Aleix Martínez-Pérez, Des C Winter, Filippo Landi, Giulio Cesare Vitali, Bertrand Le Roy, Federico Coccolini, Francesco Brunetti, Valerio Celentano, Salomone Di Saverio and 4 more

Abstract readComparative StudyMulticenter Study
PubMed Publisher
In one paragraph

Article in Surgical endoscopy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 3 pooled it
4.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 3 syntheses or guidelines pooled it, 49 citations in OpenAlex.

  1. Pooled it
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  10. SF-CORNER (splenic flexure colorectal cancer): an international survey of operative approaches and outcomes for cancers of the splenic flexure.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2024
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  12. Review
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  15. Laparoscopic versus open surgery for left flexure colon cancer: A propensity score matched analysis from an international cohort.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 8 institutions in 6 countries.

Nicola de'AngelisUnit of Digestive, Hepato-Pancreato-Biliary Surgery, Henri Mondor Hospital, AP-HP, University of Paris Est, UPEC, Créteil, France. nic.deangelis@yahoo.it.ORCID 0000-0002-1211-4916
Aleix Martínez-PérezUnit of Colorectal Surgery, Department of General and Digestive Surgery, Hospital Universitario Doctor Peset, Valencia, Spain.
Des C WinterDepartment of Surgery, St. Vincent's University Hospital, Elm Park, Dublin 4, Ireland.
Filippo LandiDepartment of General Surgery, Viladecans Hospital, Barcelona, Spain.
Giulio Cesare VitaliService of Abdominal Surgery, Geneva University Hospitals and Medical School, Geneva, Switzerland.
Bertrand Le RoyDepartment of Digestive and Hepato-Biliary Surgery, Hospital Estaing, CHU Clermont-Ferrand, Clermont-Ferrand, France.
Federico CoccoliniGeneral, Emergency and Trauma Surgery Department, Bufalini Hospital of Cesena, Cesena, Italy.
Francesco BrunettiUnit of Digestive, Hepato-Pancreato-Biliary Surgery, Henri Mondor Hospital, AP-HP, University of Paris Est, UPEC, Créteil, France.
Valerio CelentanoMinimally Invasive Colorectal Unit, Portsmouth Hospitals NHS Trust, Portsmouth, UK.
Salomone Di SaverioCambridge University Hospitals NHS Foundation Trust, Addenbrooke's Hospital, Cambridge Biomedical Campus, Cambridge, UK.
Frederic RisService of Abdominal Surgery, Geneva University Hospitals and Medical School, Geneva, Switzerland.
David FuksDepartment of Digestive Oncologic and Metabolic Surgery, Institut Mutualiste Montsouris, Paris Descartes University, Paris, France.
Eloy EspinUnit of Colorectal Surgery, Department of General and Digestive Surgery, University Hospital Vall D'Hebron, Universitat Autonoma de Barcelona, Barcelona, Spain.
SFC Study Group
Université Paris-Est Créteil · FRCambridge University Hospitals NHS Foundation Trust · GBHospital de Viladecans · ESUniversitat Autònoma de Barcelona · ESOspedale “M. Bufalini” di Cesena · ITSt. Vincent's University Hospital · IEUniversité Paris Cité · FRUniversity Hospital of Geneva · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe surgical resection of the splenic flexure carcinoma (SFC) is challenging and the optimal surgical procedure for SFCs remains a matter of debate. The present study aimed to compare in a multicenter European sample of patients the short- and long-term outcomes of extended right (ERC) vs. left (LC) vs. segmental left colectomy (SLC) for SFCs.

methodsThis retrospective multicenter study analyzed the surgical and oncological outcomes of SFC patients undergoing elective curative intent surgery between 2000 and 2018. Descriptive and exploratory analyses were first conducted on the whole sample. Outcomes of the different procedures (ERC vs. LC vs. SLC) were then compared using propensity score matching for multilevel treatment. Overall (OS) and disease-free survival (DFS) were evaluated by Kaplan-Meier method.

resultsFrom a total of 399 SFC patients, 143 (35.8%) underwent ERC, 131 (32.8%) underwent LC, and 125 (31.4%) underwent SLC. Overall, 297 (74.4%) were laparoscopic procedures. An increase in operative time, time to flatus, time to regular diet, and hospital stay was observed with the progressive extension of SFC resection. ERC was associated with significantly increased risk of postoperative ileus compared to both LC and SLC. A significantly greater number of lymph nodes were retrieved by ERC, but the objective of at least 12 retrieved lymph nodes was achieved in 85% of patients, without procedure-related differences. No differences were observed in OS or DFS between ERC, LC, and SLC.

conclusionThe present study supports the resection of SFCs by colon-sparing surgical techniques, such as SLC.

Indexed as

AdultAgedAged, 80 and overCarcinomaColectomyColonic NeoplasmsColon, TransverseDisease-Free SurvivalElective Surgical ProceduresFemaleHumansLaparoscopyLength of StayLymph NodesMaleMiddle AgedExtended right colectomyLeft colectomyPostoperative complicationsPropensity score matchingSegmental left colectomySplenic flexure carcinoma

Identifiers

PMID32072288
OpenAlexW3007193863

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.