SynthesisEuropean journal of trauma and emergency surgery : official publication of the European Trauma Society2020
A systematic review of the effect of regional anesthesia on diagnosis and management of acute compartment syndrome in long bone fractures.
Synthesis in European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 27 citations in OpenAlex.
- Compartment Syndrome of the Pediatric Upper Extremity: Current Concepts.Children (Basel, Switzerland) · 2025Review
- Integrating Peripheral Nerve Blocks in Multiple Trauma Care: Current Evidence and Clinical Challenges.Journal of clinical medicine · 2025Review
- Carbon footprint in trauma surgery, is there a way to reduce it?Journal of anesthesia, analgesia and critical care · 2024Article
- The Impact of Regional Anesthesia in Masking Acute Compartment Syndrome after Limb Trauma.Journal of clinical medicine · 2024Review
- Regional anesthesia improves inpatient but not outpatient opioid demand in tibial shaft fracture surgery.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2023Article
- Regional anesthesia provides limited decreases in opioid use following distal tibia and ankle fracture surgery.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2023Article
- Pain Control with Regional Anesthesia in Patients at Risk of Acute Compartment Syndrome: Review of the Literature and Editorial View.Journal of pain research · 2023Review
- Regional anesthesia does not decrease inpatient or outpatient opioid demand in distal femur fracture surgery.Archives of orthopaedic and trauma surgery · 2022Article
- Emergency Department Utilization After Administration of Peripheral Nerve Blocks for Upper Extremity Surgery.Hand (New York, N.Y.) · 2022Review
- Article
- Ultrasound-Guided Nerve Blocks: Suggested Procedural Guidelines for Emergency Physicians.POCUS journal · 2022Article
- Extremity compartment syndrome: A review with a focus on non-invasive methods of diagnosis.Frontiers in bioengineering and biotechnology · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposePeripheral nerve blockade (PNB) is a useful tool for pain control in the perioperative period. However, there are significant concerns about the use of PNBs following acute orthopaedic trauma due to the theoretical risk of masking acute compartment syndrome (ACS). This study aims to systematically review the effects of PNBs on diagnosis of ACS following long bone fractures.
methodsA systematic review of the literature was conducted according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines.
resultsSix studies, all of which were single-patient case reports, met criteria for inclusion in this review. Two studies reported a delay in diagnosis of ACS in the setting of PNB use, while four studies did not.
conclusionsDue to the low incidence of ACS, there is a paucity of literature available on ACS following PNB use in the setting of orthopedic trauma. There is no consensus in the literature about the safety of PNB use in the setting of acute long bone fractures, and this review could draw no conclusions from the literature, as the level of evidence is limited to case reports. PNBs should be administered to orthopedic trauma patients only in strictly controlled research environments, and surgeons should be highly cautious about using PNBs for orthopedic long bone fractures, particularly in cases at increased risk for developing ACS.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.