Evidence map›Paper›PMID 32072187›Full record

ArticleMicrobial ecology2020

Antibiotic Activity of Wickerhamomyces anomalus Mycocins on Multidrug-Resistant Acinetobacter baumannii.

Daniele S B Junges, Mateus F Delabeneta, Lana Rubia B Rosseto, Bruna L Nascimento, Ana Paula Paris, Cristiane Persel, Eduardo A Loth, Rita C G Simão, Rafael A Menolli, Claudete R Paula and 1 more

Abstract read
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In one paragraph

Article in Microbial ecology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Antimicrobial activity of immobilized mycocins in sodium alginate on fecal coliforms.Water science and technology : a journal of the International Association on Water Pollution Research · 2025
    Article
  4. Probiotic Yeasts: A Developing Reality?Journal of fungi (Basel, Switzerland) · 2024
    Review
  5. Article
  6. Article
  7. Article
  8. Toxins · 2021
    Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Daniele S B JungesWestern Paraná University Hospital, Western Paraná State University, Cascavel, Paraná, 85806-470, Brazil.
Mateus F DelabenetaWestern Paraná University Hospital, Western Paraná State University, Cascavel, Paraná, 85806-470, Brazil.
Lana Rubia B RossetoWestern Paraná University Hospital, Western Paraná State University, Cascavel, Paraná, 85806-470, Brazil.
Bruna L NascimentoWestern Paraná University Hospital, Western Paraná State University, Cascavel, Paraná, 85806-470, Brazil.
Ana Paula ParisWestern Paraná University Hospital, Western Paraná State University, Cascavel, Paraná, 85806-470, Brazil.
Cristiane PerselWestern Paraná University Hospital, Western Paraná State University, Cascavel, Paraná, 85806-470, Brazil.
Eduardo A LothWestern Paraná University Hospital, Western Paraná State University, Cascavel, Paraná, 85806-470, Brazil.
Rita C G SimãoCenter of Medical and Pharmaceutical Sciences, Western Paraná State University, Cascavel, Paraná, 85819-110, Brazil.
Rafael A MenolliCenter of Medical and Pharmaceutical Sciences, Western Paraná State University, Cascavel, Paraná, 85819-110, Brazil.
Claudete R PaulaFaculty of Odontology, University of São Paulo, Butantã, São Paulo, 05508-000, Brazil.
Rinaldo F GandraWestern Paraná University Hospital, Western Paraná State University, Cascavel, Paraná, 85806-470, Brazil. rinaldo.gandra@unioeste.br.ORCID https://orcid.org/0000-0001-9586-7253

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To evaluate the susceptibility of multidrug-resistant Acinetobacter baumannii to mycocins produced by Wickerhamomyces anomalus and to verify the cytotoxicity of these compounds. Three culture supernatants of W. anomalus (WA40, WA45, and WA92), containing mycocins (WA40M1, WA45M2, and WA92M3), were tested on A. baumannii using broth microdilution methods, solid medium tests, and cytotoxicity tests in human erythrocytes and in Artemia saline Leach. W. anomalus was able to produce high antimicrobial mycocins, as even at high dilutions, they inhibited A. baumannii. In a solid medium, it was possible to observe the inhibition of A. baumannii, caused by the diffusion of mycocins between agar. Finally, the three supernatants were not cytotoxic when tested on human erythrocytes and Artemia salina. According to the evidence in this study, the mycocins of W. anomalus have been effective and could be used in the development of new antimicrobial substances.

Indexed as

Acinetobacter baumanniiAnimalsAnti-Infective AgentsArtemiaErythrocytesHumansSaccharomycetalesAnti-Infective AgentsAcinetobacter baumanniiAntibioticsKiller yeastsMultidrug resistanceMycocinsWickerhamomyces anomalus

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.