Evidence map›Paper›PMID 32071939›Full record

ArticleMovement disorders clinical practice2020

Localization of Salivary Glands for Botulinum Toxin Treatment: Ultrasound Versus Landmark Guidance.

Sebastian Loens, Norbert Brüggemann, Armin Steffen, Tobias Bäumer

Abstract read
In one paragraph

Article in Movement disorders clinical practice, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Localization modalities for botulinum neurotoxin injection.Toxicon : official journal of the International Society on Toxinology · 2025
    Review
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sebastian LoensInstitute of Neurogenetics University of Luebeck Luebeck Germany.
Norbert BrüggemannInstitute of Neurogenetics University of Luebeck Luebeck Germany.ORCID https://orcid.org/0000-0001-5969-6899
Armin SteffenDepartment for Otorhinolaryngology University of Luebeck Luebeck Germany.
Tobias BäumerInstitute of Neurogenetics University of Luebeck Luebeck Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSialorrhea is a troublesome symptom in a variety of neurological diseases. Recently, local injection of botulinum toxin into the salivary glands was approved for treatment of sialorrhea, and injection guidance by anatomical landmarks was suggested.

objectiveTo compare the accuracy of ultrasound versus previously proposed anatomical landmarks for localizing the salivary glands.

methodsIn a cross-sectional study in 21 adults, landmark positions (LM) of the parotid gland (PG) and the submandibular gland (SG) were identified following published recommendations. The ultrasound position (US) was defined as the position representing the maximum gland thickness. The distance between positions, gland thickness, and optimal injection depth were recorded by US.

resultsGland thickness differed significantly between LM and US positions (PG, 4 vs. 17.8 mm;

conclusionsThe position of the salivary glands differs from proposed landmarks and depends on the individual age and body weight; therefore, we recommend ultrasound guidance for injection.

Indexed as

botulinum toxinhypersalivationsialorrheaultrasound

Identifiers

PMID32071939
PMCPMC7011800

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.