Evidence map›Paper›PMID 32071928›Full record

ArticleMolecular therapy. Methods & clinical development2020

CAR T Cell Generation by

David C Bishop, Lisa Caproni, Kavitha Gowrishankar, Michal Legiewicz, Kinga Karbowniczek, John Tite, David J Gottlieb, Kenneth P Micklethwaite

Open access · goldAbstract read
In one paragraph

Article in Molecular therapy. Methods & clinical development, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 30 citations in OpenAlex.

  1. Review
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  8. Characterizing piggyBat-a transposase for genetic modification of T cells.Molecular therapy. Methods & clinical development · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

David C BishopWestmead Institute for Medical Research, Sydney, NSW, Australia.
Lisa CaproniTouchlight Genetics, Hampton, United Kingdom.
Kavitha GowrishankarWestmead Institute for Medical Research, Sydney, NSW, Australia.
Michal LegiewiczTouchlight Genetics, Hampton, United Kingdom.
Kinga KarbowniczekTouchlight Genetics, Hampton, United Kingdom.
John TiteTouchlight Genetics, Hampton, United Kingdom.
David J GottliebWestmead Institute for Medical Research, Sydney, NSW, Australia.
Kenneth P MicklethwaiteWestmead Institute for Medical Research, Sydney, NSW, Australia.
The University of Sydney · AUWestmead Hospital · AUWestmead Institute for Medical Research · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CD19-specific chimeric antigen receptor (CAR19) T cells, generated using viral vectors, are an efficacious but costly treatment for B cell malignancies. The nonviral

Indexed as

B cell malignancyCARCD19Chimeric antigen receptordoggybonelinear DNA vectorminimal DNA vectornon-viral vectorpiggyBac transposonT cell immunotherapy

Identifiers

PMID32071928
PMCPMC7016334
OpenAlexW2999769282

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.