ArticleChemistryOpen2019
Supramolecular Tandem Assay for Pyridoxal-5'-phosphate by the Reporter Pair of Guanidinocalix[5]Arene and Fluorescein.
Article in ChemistryOpen, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed.
- Facile calixarene-based sensor array strategy for quality evaluation of Yinxing Mihuan oral solution.RSC advances · 2025Article
- Recent Advances in Calixarene-Based Fluorescent Sensors for Biological Applications.Sensors (Basel, Switzerland) · 2024Review
- Enzyme assays with supramolecular chemosensors - the label-free approach.RSC advances · 2022Review
- Recent advances in macrocyclic arenes-based fluorescent indicator displacement assays.Frontiers in chemistry · 2022Review
- Supramolecular Tandem Assay for Pyridoxal-5'-phosphate by the Reporter Pair of Guanidinocalix[5]Arene and Fluorescein.ChemistryOpen · 2019Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Guanidinocalix[5]arene and fluorescein reporter pair has been chosen to set up a supramolecular tandem assay principle based on the differential recognition of pyridoxal-5'-phosphate (the substrate of alkaline phosphatase, ALP), pyridoxal (the product of ALP) and phosphate (the product of ALP). This supramolecular tandem assay system offers an opportunity to monitor the activity of ALP in a label-free, continuous, and real-time manner. More importantly, a calibration curve can be given for selective and quantitative detection of pyridoxal-5'-phosphate (biomarker for several diseases).
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Registered trials
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