Evidence map›Paper›PMID 32071675›Full record

ArticleACS medicinal chemistry letters2020

Reinvestigation of Mycothiazole Reveals the Penta-2,4-dien-1-ol Residue Imparts Picomolar Potency and 8

Tyler A Johnson, Joseph D Morris, David A Coppage, Colon V Cook, Lauren N Persi, Marcos A Ogarrio, Taylor C Garcia, Nicole L McIntosh, Erin P McCauley, Joseph Media and 4 more

Abstract read
In one paragraph

Article in ACS medicinal chemistry letters, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Form and function of actin impacts actin health and aging.bioRxiv : the preprint server for biology · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Natural Products from Tongan Marine Organisms.Molecules (Basel, Switzerland) · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Tyler A JohnsonDepartment of Natural Sciences & Mathematics, Dominican University of California, San Rafael, California 94901, United States.
Joseph D MorrisDepartment of Natural Sciences & Mathematics, Dominican University of California, San Rafael, California 94901, United States.
David A CoppageDepartment of Chemistry & Biochemistry, University of California, Santa Cruz, Santa Cruz, California 95064, United States.
Colon V CookDepartment of Natural Sciences & Mathematics, Dominican University of California, San Rafael, California 94901, United States.
Lauren N PersiDepartment of Natural Sciences & Mathematics, Dominican University of California, San Rafael, California 94901, United States.
Marcos A OgarrioDepartment of Natural Sciences & Mathematics, Dominican University of California, San Rafael, California 94901, United States.
Taylor C GarciaDepartment of Natural Sciences & Mathematics, Dominican University of California, San Rafael, California 94901, United States.
Nicole L McIntoshDepartment of Natural Sciences & Mathematics, Dominican University of California, San Rafael, California 94901, United States.
Erin P McCauleyDepartment of Chemistry & Biochemistry, University of California, Santa Cruz, Santa Cruz, California 95064, United States.
Joseph MediaJosephine Ford Cancer Center, Division of Hematology and Oncology, Department of Internal Medicine, Henry Ford Health System, Detroit, Michigan 48202, United States.
Mani MaheshwariJosephine Ford Cancer Center, Division of Hematology and Oncology, Department of Internal Medicine, Henry Ford Health System, Detroit, Michigan 48202, United States.
Frederick A ValerioteJosephine Ford Cancer Center, Division of Hematology and Oncology, Department of Internal Medicine, Henry Ford Health System, Detroit, Michigan 48202, United States.
Jiajiu Shaw21st Century Therapeutics, 440 Burroughs, Suite 447, Detroit, Michigan 48202, United States.
Phillip CrewsDepartment of Chemistry & Biochemistry, University of California, Santa Cruz, Santa Cruz, California 95064, United States.

Funding

NOVEL CYTOTOXIC NATURAL PRODUCTS FROM MARINE SPONGESR01CA047135 · NCI · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI CREWS, PHIL, VALERIOTE, FREDERICK AUGUSTUS · 1989 to 2017
$8.1M
Acquisition of a Cryoprobe and Related Accessories for a 600 MHz NMR Spectrometer to Support Health Research Activities at the University of California, BerkeleyS10OD024998 · OD · UNIVERSITY OF CALIFORNIA BERKELEY · PI HARTWIG, JOHN F · 2018 to 2018
$265k
NCI NIH HHS R01 CA047135NIH HHS S10 OD024998
6 · The paper itself

Abstract

Reinvestigation of mycothiazole (

Identifiers

PMID32071675
PMCPMC7025380

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.