Evidence map›Paper›PMID 32071628›Full record

ArticleJournal of arrhythmia2020

Association of QT dispersion with mortality and arrhythmic events-A meta-analysis of observational studies.

George Bazoukis, Cynthia Yeung, Ryan Wui Hang Ho, Dimitrios Varrias, Stamatis Papadatos, Sharen Lee, Ka Ho Christien Li, Antigoni Sakellaropoulou, Athanasios Saplaouras, Panagiotis Kitsoulis and 6 more

Abstract read
In one paragraph

Article in Journal of arrhythmia, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Cardiac Manifestations in Behçet's Syndrome.Current rheumatology reports · 2025
    Review
  6. Evaluation of Arrhythmia Risk in Children with Type 1 Diabetes MellitusJournal of clinical research in pediatric endocrinology · 2025
    Article
  7. Article
  8. QTc Interval Dispersion in Pediatric Epilepsy: A Case-Control Study From Iran.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2025
    Article
  9. Review
  10. Article
  11. Electrocardiographic characteristics of bladder cancer patients receiving preoperative chemotherapy combined with immunotherapy.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2024
    Article
  12. Article
  13. Article
  14. Article
  15. Comparison of QT dispersion before and after PDA device closure in pediatrics.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2022
    Article
  16. Article
  17. Article
  18. Correlation Between QTc Prolongation and Obstructive Sleep Apnea in Patients with Type 2 Diabetes Mellitus.Medical science monitor : international medical journal of experimental and clinical research · 2020
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

George BazoukisSecond Department of Cardiology Laboratory of Cardiac Electrophysiology "Evangelismos" General Hospital of Athens Athens Greece.ORCID https://orcid.org/0000-0003-1009-9772
Cynthia YeungDepartment of Medicine Queen's University Kingston ON Canada.ORCID https://orcid.org/0000-0001-8263-4290
Ryan Wui Hang HoLi Ka Shing Faculty of Medicine University of Hong Kong Hong Kong P.R. China.
Dimitrios VarriasHarvard Medical School Boston MA USA.
Stamatis Papadatos3rd Department of Internal Medicine Sotiria General Hospital National and Kapodistrian University of Athens Medical School Athens Greece.
Sharen LeeLaboratory of Cardiovascular Physiology Li Ka Shing Institute of Health Sciences Hong Kong S.A.R. P.R. China.
Ka Ho Christien LiFaculty of Medicine Newcastle University Newcastle UK.
Antigoni SakellaropoulouSecond Department of Cardiology Laboratory of Cardiac Electrophysiology "Evangelismos" General Hospital of Athens Athens Greece.
Athanasios SaplaourasSecond Department of Cardiology Laboratory of Cardiac Electrophysiology "Evangelismos" General Hospital of Athens Athens Greece.
Panagiotis KitsoulisLaboratory of Anatomy-Histology-Embryology School of Medicine University of Ioannina Ioannina Greece.
Konstantinos VlachosSecond Department of Cardiology Laboratory of Cardiac Electrophysiology "Evangelismos" General Hospital of Athens Athens Greece.
Konstantinos LampropoulosSecond Department of Cardiology Laboratory of Cardiac Electrophysiology "Evangelismos" General Hospital of Athens Athens Greece.
Costas ThomopoulosDepartment of Cardiology Helena Venizelou Hospital Athens Greece.
Konstantinos P LetsasSecond Department of Cardiology Laboratory of Cardiac Electrophysiology "Evangelismos" General Hospital of Athens Athens Greece.
Tong LiuTianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular disease Department of Cardiology Tianjin Institute of Cardiology Second Hospital of Tianjin Medical University Tianjin China.
Gary TseLaboratory of Cardiovascular Physiology Li Ka Shing Institute of Health Sciences Hong Kong S.A.R. P.R. China.ORCID https://orcid.org/0000-0001-5510-1253

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe risk stratification of coronary heart disease (CHD) and/or heart failure (HF) patients with easily measured electrocardiographic markers is of clinical importance. The aim of this meta-analysis is to indicate whether increased QT dispersion (QTd) is associated with fatal and nonfatal outcomes in patients with CHD and/or HF.

methodsWe systematically searched MEDLINE and Cochrane databases without restrictions until August 15, 2018 using the keyword "QT dispersion". Studies including data on the association between QTd and all-cause mortality, sudden cardiac death (SCD) or arrhythmic events in patients with HF and/or CHD were classified as eligible.

resultsIn the analysis including patients with CHD and/or HF, we found that QTd did not differ significantly in patients with SCD compared to no SCD patients while QTd was significantly greater in the group of all-cause mortality patients and in patients who experienced a sustained ventricular arrhythmia. Subgroup analysis showed that in myocardial infarction studies, QTd was significantly higher in patients with an arrhythmic event compared to arrhythmic event-free patients while a nonsignificant difference was found in QTd in patients who died from any cause compared to survivors. Similarly, in HF patients, the QTd was significantly greater in patients with an arrhythmic event while a nonsignificant difference was found regarding all-cause mortality and SCD outcomes.

conclusionsQTd has a prognostic role for stratifying myocardial infarction or HF patients who are at higher risk of arrhythmic events. However, no prognostic role was found regarding all-cause mortality or SCD in this patient population.

Indexed as

all‐cause mortalityarrhythmic eventscoronary artery diseaseheart failureQT dispersion

Identifiers

PMID32071628
PMCPMC7011802

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.