ArticleScientific reports2020
One year structural and functional glaucoma progression after trabeculectomy.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06174324 (Visual Field Progression and RNFL Change After PreserFlo MicroShunt Implantation - a Prospective Cohort Study at the Ophthalmology Department Klinikum Klagenfurt), which is not on this map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Visual Field Progression and RNFL Change After PreserFlo MicroShunt Implantation - a Prospective Cohort Study at the Ophthalmology Department Klinikum Klagenfurt
Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- PreserFlo MicroShunt versus trabeculectomy: an updated meta-analysis and systematic review.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025Pooled it
- Evaluation of Posterior Segment Structural and Vascular Changes After Gonioscopy-Assisted Transluminal Trabeculotomy.Diagnostics (Basel, Switzerland) · 2026Article
- The Impact of Clinical Success Levels on Postoperative RNFL Development After Trabeculectomy.Vision (Basel, Switzerland) · 2026Article
- Longitudinal OCT changes of the peripapillary RNFL after different glaucoma interventions - a comparative study.BMC ophthalmology · 2026Article
- Performance of OCT-Based Artificial Intelligence Models for Detecting and Predicting Glaucoma Progression: A Systematic Review.Journal of clinical medicine · 2026Review
- Functional and Morphological Outcomes after Trabeculectomy and Deep Sclerectomy-Results from a Monocentric Registry Study.Diagnostics (Basel, Switzerland) · 2024Article
- PRESERFLO MicroShunt implantation versus trabeculectomy for primary open-angle glaucoma: a two-year follow-up study.Eye and vision (London, England) · 2023Article
- Predicting glaucoma progression using deep learning framework guided by generative algorithm.Scientific reports · 2023Article
- Two Year Functional and Structural Changes-A Comparison between Trabeculectomy and XEN Microstent Implantation Using Spectral Domain Optical Coherence Tomography.Journal of clinical medicine · 2022Article
- Ganglion Cell Complex: The Optimal Measure for Detection of Structural Progression in the Macula.American journal of ophthalmology · 2022Article
- Estimating Ganglion Cell Complex Rates of Change With Bayesian Hierarchical Models.Translational vision science & technology · 2021Article
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We evaluated the changes in visual field mean deviation (VF MD) and retinal nerve fibre layer (RNFL) thickness in glaucoma patients undergoing trabeculectomy. One hundred patients were examined with VF and spectral-domain optical coherence tomography (OCT) before trabeculectomy and 4 follow-up visits over one year. Linear mixed models were used to investigate factors associated with VF and RNFL. VF improved during the first 3 months of follow-up (2.55 ± 1.06 dB/year) and worsened at later visits (-1.14 ± 0.29 dB/year). RNFL thickness reduced by -4.21 ± 0.25 µm/year from 1st month of follow-up. Eyes with an absence of initial VF improvement (β = 0.64; 0.30-0.98), RNFL thinning (β = 0.15; 0.08-0.23), increasing intraocular pressure (IOP; β = -0.11; -0.18 to -0.03) and severe glaucoma (β = -10.82; -13.61 to -8.02) were associated with VF deterioration. Eyes with VF deterioration (β = 0.19; 0.08-0.29), increasing IOP (β = -0.09; -0.17 to -0.01), and moderate (β = -6.33; -12.17 to -0.49) or severe glaucoma (β = -19.58; -24.63 to -14.52) were associated with RNFL thinning. Changes in RNFL structure and function occur over a 1-year follow-up period after trabeculectomy. Early VF improvement is more likely to occur in patients with mild/moderate glaucoma, whereas those with severe glaucoma show greater decline over one year. Our findings indicate that progression is observable using OCT, even in late-stage glaucoma.
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