Evidence map›Paper›PMID 32071283›Full record

ArticleJournal of clinical medicine2020

Sequential Circulating Tumor Cell Counts in Patients with Locally Advanced or Metastatic Hepatocellular Carcinoma: Monitoring the Treatment Response.

Kun-Ming Rau, Chien-Ting Liu, Yu-Chiao Hsiao, Kai-Yin Hsiao, Tzu-Min Wang, Wei-Shan Hung, Yu-Li Su, Wei-Ching Liu, Cheng-Hsu Wang, Hsueh-Ling Hsu and 3 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 41 citations in OpenAlex.

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  13. Biomarkers for hepatocellular carcinoma based on body fluids and feces.World journal of gastrointestinal oncology · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Kun-Ming RauDepartment of Hematology-Oncology, E-Da Cancer Hospital, Kaohsiung 824, Taiwan.ORCID 0000-0002-1209-3043
Chien-Ting LiuDivision of Hematology-Oncology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung 833, Taiwan.
Yu-Chiao HsiaoDepartment of Medical Biotechnology and Laboratory Science, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan.
Kai-Yin HsiaoDivision of Hematology-Oncology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung 833, Taiwan.
Tzu-Min WangDepartment of Medical Biotechnology and Laboratory Science, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan.
Wei-Shan HungDepartment of Medical Biotechnology and Laboratory Science, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan.
Yu-Li SuDivision of Hematology-Oncology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung 833, Taiwan.ORCID 0000-0002-1289-473X
Wei-Ching LiuDivision of Hematology-Oncology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung 833, Taiwan.
Cheng-Hsu WangCollege of Medicine, Chang Gung University, Taoyuan 333, Taiwan.
Hsueh-Ling HsuDepartment of Medical Biotechnology and Laboratory Science, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan.
Po-Heng ChuangDepartment of Internal Medicine, China Medical University Hospital, Taichung 404, Taiwan.ORCID 0000-0003-3711-5445
Ju-Chien ChengDepartment of Medical Laboratory Science and Biotechnology, China Medical University, Taichung 404, Taiwan.
Ching-Ping TsengDepartment of Medical Biotechnology and Laboratory Science, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan.
Chang Gung University · TWChina Medical University · TWKaohsiung Chang Gung Memorial Hospital · TWE-Da Hospital · TW

Funding

Chang Gung Medical Foundation CMRPD1E0181-3, CMRPD1F0611-3, CMRPD1H0211-3, and BMRP466Chang Gung Molecular Medicine Research Center EMRPD1G0081China Medical University Hospital DMR-106-021Ministry of Science and Technology 105-2320-B-182-029-MY3, 106-2320-B-182-027-MY3, and 105-2314-B-182-042
6 · The paper itself

Abstract

Hepatocellular carcinoma (HCC) is among the most common causes of cancer death in men. Whether or not a longitudinal follow-up of circulating tumor cells (CTCs) before and at different time points during systemic/targeted therapy is useful for monitoring the treatment response of patients with locally advanced or metastatic HCC has been evaluated in this study. Blood samples (

Indexed as

alpha-fetoproteincirculating tumor cellshepatocellular carcinomalongitudinal follow-up

Identifiers

PMID32071283
PMCPMC7019972
OpenAlexW2999782024

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.