ArticlemBio2020
New Pathogenesis Mechanisms and Translational Leads Identified by Multidimensional Analysis of Necrotizing Myositis in Primates.
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Article in mBio, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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16citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
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Who cites it
16 citing papers in PubMed, 27 citations in OpenAlex.
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- Analysis of host-pathogen gene association networks reveals patient-specific response to streptococcal and polymicrobial necrotising soft tissue infections.BMC medicine · 2022Article
- CovS inactivation reduces CovR promoter binding at diverse virulence factor encoding genes in group A Streptococcus.PLoS pathogens · 2022Article
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- Genome-wide analysis of in vivo CcpA binding with and without its key co-factor HPr in the major human pathogen group A Streptococcus.Molecular microbiology · 2021Article
- Genital Tract GAS Infection ISIDOG Guidelines.Journal of clinical medicine · 2021Review
- DualSeqDB: the host-pathogen dual RNA sequencing database for infection processes.Nucleic acids research · 2021Article
- Cellular Growth Arrest and Efflux Pumps Are Associated With Antibiotic Persisters inFrontiers in microbiology · 2021Article
- Single Amino Acid Replacements in RocA Disrupt Protein-Protein Interactions To Alter the Molecular Pathogenesis of Group AInfection and immunity · 2020Article
- Streptococcus pyogenes genes that promote pharyngitis in primates.JCI insight · 2020Article
Corrections and comments
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Authors and funding
17 authors at 4 institutions in 3 countries.
Priyanka Kachroo *Center for Molecular and Translational Human Infectious Diseases Research, Department of Pathology and Genomic Medicine, Houston Methodist Research Institute and Houston Methodist Hospital, Houston, Texas, USA.ORCID 0000-0002-3563-7832
Jesus M Eraso *Center for Molecular and Translational Human Infectious Diseases Research, Department of Pathology and Genomic Medicine, Houston Methodist Research Institute and Houston Methodist Hospital, Houston, Texas, USA.ORCID 0000-0003-1383-8702
Randall J Olsen *Center for Molecular and Translational Human Infectious Diseases Research, Department of Pathology and Genomic Medicine, Houston Methodist Research Institute and Houston Methodist Hospital, Houston, Texas, USA.
Luchang Zhu *Center for Molecular and Translational Human Infectious Diseases Research, Department of Pathology and Genomic Medicine, Houston Methodist Research Institute and Houston Methodist Hospital, Houston, Texas, USA.
Samantha L KubiakCenter for Molecular and Translational Human Infectious Diseases Research, Department of Pathology and Genomic Medicine, Houston Methodist Research Institute and Houston Methodist Hospital, Houston, Texas, USA.
Layne PruittCenter for Molecular and Translational Human Infectious Diseases Research, Department of Pathology and Genomic Medicine, Houston Methodist Research Institute and Houston Methodist Hospital, Houston, Texas, USA.
Prasanti YerramilliCenter for Molecular and Translational Human Infectious Diseases Research, Department of Pathology and Genomic Medicine, Houston Methodist Research Institute and Houston Methodist Hospital, Houston, Texas, USA.
Concepcion C CantuCenter for Molecular and Translational Human Infectious Diseases Research, Department of Pathology and Genomic Medicine, Houston Methodist Research Institute and Houston Methodist Hospital, Houston, Texas, USA.
Matthew Ojeda SaavedraCenter for Molecular and Translational Human Infectious Diseases Research, Department of Pathology and Genomic Medicine, Houston Methodist Research Institute and Houston Methodist Hospital, Houston, Texas, USA.
Johan PensarDepartment of Mathematics and Statistics, Helsinki Institute of Information Technology, University of Helsinki, Helsinki, Finland.
Jukka CoranderDepartment of Mathematics and Statistics, Helsinki Institute of Information Technology, University of Helsinki, Helsinki, Finland.
Leslie JenkinsComparative Medicine Program, Houston Methodist Research Institute, Houston, Texas, USA.
Lillian KaoDepartment of Surgery, University of Texas McGovern Medical School, Houston, Texas, USA.
Alejandro GranilloDepartment of Internal Medicine, Houston Methodist Research Institute and Houston Methodist Hospital, Houston, Texas, USA.
Adeline R PorterLaboratory of Bacteriology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, USA.
Frank R DeLeoLaboratory of Bacteriology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, USA.
James M MusserCenter for Molecular and Translational Human Infectious Diseases Research, Department of Pathology and Genomic Medicine, Houston Methodist Research Institute and Houston Methodist Hospital, Houston, Texas, USA jmmusser@houstonmethodist.org.ORCID 0000-0002-7765-4956
Houston Methodist · USNational Institutes of Health · USUniversity of Helsinki · FIThe University of Texas Health Science Center at Houston · US
Funding
Interaction of pathogenic bacteria with human phagocytic leukocytesZIAAI000900 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI DELEO, FRANK · 2009 to 2023
$3.6MDeterminants of Streptococcus pyogenes virulence in the primate oropharynx: A genome-wide analysisR21AI139369 · NIAID · METHODIST HOSPITAL RESEARCH INSTITUTE · PI MUSSER, JAMES MALLORY · 2019 to 2020
$444kDeterminants of Streptococcus pyogenes fitness in the female primate genital tract: A genome-wide analysisR21AI146771 · NIAID · METHODIST HOSPITAL RESEARCH INSTITUTE · PI MUSSER, JAMES MALLORY · 2019 to 2020
$444kNIAID NIH HHS R21 AI139369NIAID NIH HHS R21 AI146771
Abstract
A fundamental goal of contemporary biomedical research is to understand the molecular basis of disease pathogenesis and exploit this information to develop targeted and more-effective therapies. Necrotizing myositis caused by the bacterial pathogen
Indexed as
TranscriptomeAnimalsBacterial ProteinsFasciitis, NecrotizingGene Expression Regulation, BacterialHost-Pathogen InteractionsMuscle, SkeletalMyositisPrimatesRNA, BacterialStreptococcal InfectionsStreptococcus pyogenesVirulenceVirulence FactorsBacterial ProteinsRNA, BacterialVirulence Factorsbacterial pathogenesisbacterial virulencedual RNA-seqnecrotizing fasciitispathogen-host interactionStreptococcus pyogenes
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.