Evidence map›Paper›PMID 32071204›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2020

Foxn4 is a temporal identity factor conferring mid/late-early retinal competence and involved in retinal synaptogenesis.

Shuting Liu, Xiaoning Liu, Shengguo Li, Xiuting Huang, Haohua Qian, Kangxin Jin, Mengqing Xiang

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 52 citations in OpenAlex.

  1. Article
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  4. Foxn3 is required to suppress aberrant ciliogenesis in nonphotoreceptor retinal neurons.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  5. Timing neural development and regeneration.Current opinion in neurobiology · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Temporal regulation of neural diversity in Drosophila and vertebrates.Seminars in cell & developmental biology · 2023
    Review
  12. Review
  13. Article
  14. Article
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Shuting LiuState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, 510060 Guangzhou, China.
Xiaoning LiuState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, 510060 Guangzhou, China.
Shengguo LiCenter for Advanced Biotechnology and Medicine, Rutgers Robert Wood Johnson Medical School, Piscataway, NJ 08854.
Xiuting HuangState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, 510060 Guangzhou, China.
Haohua QianVisual Function Core, National Eye Institute, National Institutes of Health, Bethesda, MD 20892.
Kangxin JinState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, 510060 Guangzhou, China; jinkx@mail.sysu.edu.cn xiangmq3@mail.sysu.edu.cn.
Mengqing XiangState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, 510060 Guangzhou, China; jinkx@mail.sysu.edu.cn xiangmq3@mail.sysu.edu.cn.
Sun Yat-sen University · CNJohnson University · USNational Eye Institute · US

Funding

Visual Function CoreZICEY000503 · NEI · NATIONAL EYE INSTITUTE · PI QIAN, HAOHUA · 2011 to 2025
$12.3M
6 · The paper itself

Abstract

During development, neural progenitors change their competence states over time to sequentially generate different types of neurons and glia. Several cascades of temporal transcription factors (tTFs) have been discovered in

Indexed as

AnimalsDNA-Binding ProteinsDrosophilaEye ProteinsForkhead Transcription FactorsGene Expression Regulation, DevelopmentalIkaros Transcription FactorMiceMice, Knockout, ApoENeurogenesisNeurogliaRetinaRetinal Cone Photoreceptor CellsRetinal Rod Photoreceptor CellsRNA-SeqSequence AnalysisCASZ1 protein, mouseDNA-Binding ProteinsEye ProteinsForkhead Transcription FactorsFoxn4 protein, mouseIkaros Transcription FactorTranscription FactorsZfpn1a1 protein, mouseFoxn4photoreceptorretinal progenitorsynaptogenesistemporal transcription factor

Identifiers

PMID32071204
PMCPMC7060670
OpenAlexW3008466048

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.