Evidence map›Paper›PMID 32071117›Full record

Trial reportClinical cancer research : an official journal of the American Association for Cancer Research2020

The Effects of a Remote-based Weight Loss Program on Adipocytokines, Metabolic Markers, and Telomere Length in Breast Cancer Survivors: the POWER-Remote Trial.

Cesar A Santa-Maria, Janelle W Coughlin, Dipali Sharma, Mary Armanios, Amanda L Blackford, Colleen Schreyer, Arlene Dalcin, Ashley Carpenter, Gerald J Jerome, Deborah K Armstrong and 12 more

Open access · bronzeAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Clinical cancer research : an official journal of the American Association for Cancer Research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 6 pooled it
1.8field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 6 syntheses or guidelines pooled it, 43 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Benefits of weight loss programs for breast cancer survivors: a systematic reviews and meta-analysis of randomized controlled trials.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Pooled it
  7. Trial
  8. Trial
  9. Trial
  10. Trial
  11. Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 2 institutions in 1 country.

Cesar A Santa-MariaDepartment of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland.ORCID 0000-0003-0979-8787
Janelle W CoughlinDepartment of Psychiatry, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Dipali SharmaDepartment of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Mary ArmaniosDepartment of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Amanda L BlackfordDepartment of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland.ORCID 0000-0002-6519-4833
Colleen SchreyerDepartment of Psychiatry, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Arlene DalcinThe Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Ashley CarpenterDepartment of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Gerald J JeromeDivision of General Internal Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland.
Deborah K ArmstrongDepartment of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Madhu ChaudhryGreater Baltimore Medical Center, Baltimore, Maryland.
Gary I CohenGreater Baltimore Medical Center, Baltimore, Maryland.
Roisin M ConnollyDepartment of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland.
John FettingDepartment of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Robert S MillerDepartment of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland.ORCID 0000-0003-0869-6316
Karen L SmithDepartment of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Claire SnyderDepartment of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Andrew WolfeDepartment of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland.ORCID 0000-0003-1120-1679
Antonio C WolffDepartment of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland.ORCID 0000-0003-3734-1063
Chiung-Yu HuangDepartment of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland.ORCID 0000-0003-2313-3562
Lawrence J AppelDepartment of Psychiatry, Johns Hopkins University School of Medicine, Baltimore, Maryland.ORCID 0000-0002-0673-6823
Vered StearnsDepartment of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland. vstearn1@jhmi.edu.
Johns Hopkins University · USGreater Baltimore Medical Center · US

Funding

Translational Research Central ServicesP30CA006973 · NCI · JOHNS HOPKINS UNIVERSITY · PI ALAN KEITH MEEKER · 1985 to 2026
$208.6M
NCI NIH HHS P30 CA006973
6 · The paper itself

Abstract

purposeWe initiated a clinical trial to determine the proportion of breast cancer survivors achieving ≥5% weight loss using a remotely delivered weight loss intervention (POWER-remote) or a self-directed approach, and to determine the effects of the intervention on biomarkers of cancer risk including metabolism, inflammation, and telomere length. EXPERIMENTAL

designWomen with stage 0-III breast cancer, who completed local therapy and chemotherapy, with a body mass index ≥25 kg/m

resultsFrom 2013 to 2015, 96 women were enrolled, and 87 were evaluable for the primary analysis; 45 to POWER-remote and 42 to self-directed. At 6 months, 51% of women randomized to POWER-remote lost ≥5% of their baseline body weight, compared with 12% in the self-directed arm [OR, 7.9; 95% confidence interval (CI), 2.6-23.9;

conclusionsA remotely delivered weight loss intervention resulted in significant weight loss in breast cancer survivors, and favorable effects on several biomarkers.

Indexed as

ExerciseTelomereWeight LossAdipokinesAdultAgedBiomarkersBody Mass IndexBreast NeoplasmsCancer SurvivorsCase-Control StudiesC-Reactive ProteinFemaleFollow-Up StudiesHumansLeukocytes, MononuclearAdipokinesBiomarkersC-Reactive Protein

Identifiers

PMID32071117
PMCPMC7299780
OpenAlexW3008317534

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.