ArticleCMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne2020
Association of use of cleaning products with respiratory health in a Canadian birth cohort.
Article in CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 54 citations in OpenAlex.
- The Role of the Indoor Exposome in Food Allergy Development.Current allergy and asthma reports · 2026Review
- Trends in pediatric household cleaning product exposures before and during the COVID-19 pandemic: a national poison data system analysis (2016-2023).BMC pediatrics · 2026Article
- Breastfeeding may lessen socioeconomic disparities in child health through differences in the infant gut microbiome.Cell reports. Medicine · 2026Article
- Recommendations for Clinicians to Combat Environmental Disparities in Pediatric Asthma: A Review.Chest · 2024Review
- From Fetus to Eight: the CHILD Cohort Study.American journal of epidemiology · 2024Article
- The Impact of COVID-19 Health Measures on Adults With Multiple Chemical Sensitivity: Cross-Sectional Study.JMIR formative research · 2024Article
- Effects of Allergen Exposure and Environmental Risk Factors in Schools on Childhood Asthma.Current allergy and asthma reports · 2023Review
- Association between maternal occupational exposure to cleaning chemicals during pregnancy and childhood wheeze and asthma.Frontiers in epidemiology · 2023Article
- Risk factor for children in the pandemic: the use of cleaning products at home.GMS hygiene and infection control · 2023Article
- Risk Factors Affecting Development and Persistence of Preschool Wheezing: Consensus Document of the Emilia-Romagna Asthma (ERA) Study Group.Journal of clinical medicine · 2022Article
- Disinfection in the time of COVID: Safe solutions are critical for schools.Paediatrics & child health · 2022Article
- The relationship of early-life household air pollution with childhood asthma and lung function.European respiratory review : an official journal of the European Respiratory Society · 2022Review
- Understanding "Atmosome", the Personal Atmospheric Exposome: Comprehensive Approach.JMIR biomedical engineering · 2021Article
- Environmental Health-Related Policies and Practices of Oklahoma Licensed Early Care and Education Programs: Implications for Childhood Asthma.International journal of environmental research and public health · 2021Article
- COVID-19 and children's health in the United States: Consideration of physical and social environments during the pandemic.Environmental research · 2021Review
- Germaphobia! Does Our Relationship With and Knowledge of Biodiversity Affect Our Attitudes Toward Microbes?Frontiers in psychology · 2021Article
- Pediatric Asthma Situation in Chengdu, China, During the COVID-19 Pandemic: An Observational Study.Journal of asthma and allergy · 2021Article
- Pandemic products and volatile chemical emissions.Air quality, atmosphere, & health · 2021Article
- Mold clean-up practices vary by sociodemographic and allergy factors.Journal of environmental health · 2020Article
- Cleaning products and asthma risk: a potentially important public health concern.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2020Article
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Authors and funding
15 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundComprehensive longitudinal studies are important for understanding the complex risk factors, pathways, exposures and interactions that lead to the development and persistence of asthma. We aimed to examine associations between use of household cleaning products in early life and childhood respiratory and allergic disease using data from the Canadian Healthy Infant Longitudinal Development (CHILD) Cohort Study.
methodsWe summed responses from parental questionnaires that indicated the frequency of use of 26 household cleaning products in the homes of 2022 children from this birth cohort when they were 3-4 months of age to create a cumulative Frequency of Use Score (FUS). We used multivariable logistic regression models to assess whether frequent compared with less frequent use was associated with recurrent wheeze, atopy or asthma diagnosis, as defined by the questionnaire and clinical assessments at age 3 years. Data were collected between 2008 and 2015.
resultsChildren in homes with a higher frequency of use of cleaning products in infancy, as determined by an interquartile range increase, had higher odds of recurrent wheeze (adjusted odds ratio [OR] 1.35, 95% confidence interval [CI] 1.11-1.64), recurrent wheeze with atopy (adjusted OR 1.49, 95% CI 1.02-2.16) and asthma diagnosis (adjusted OR 1.37, 95% CI 1.09-1.70), but no increase in the odds of atopy at age 3 years (adjusted OR 1.14, 95% CI 0.96-1.35). Compared with the lowest tertile of FUS exposure, infants in the highest tertile had higher odds of acquiring asthma. Stratification of the results showed that females had higher ORs than males for all outcomes, although the
interpretationFrequent use of household cleaning products in early life was associated with an increased risk for childhood wheeze and asthma but not atopy at age 3 years. Our findings add to the understanding of how early life exposures to cleaning products may be associated with the development of allergic airway disease and help to identify household behaviours as a potential area for intervention.
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