Evidence map›Paper›PMID 32071098›Full record

ReviewJournal of bacteriology2020

The Potential for Redox-Active Metabolites To Enhance or Unlock Anaerobic Survival Metabolisms in Aerobes.

John A Ciemniecki, Dianne K Newman

Open access · greenAbstract readReview
In one paragraph

Review in Journal of bacteriology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 42 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. The adaptability ofFrontiers in cellular and infection microbiology · 2025
    Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Identification of Key Factors for Anoxic Survival ofInternational journal of molecular sciences · 2022
    Article
  17. Article
  18. Functional Analysis of Phenazine Biosynthesis Genes inApplied and environmental microbiology · 2021
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

John A CiemnieckiDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, California, USA.ORCID 0000-0003-2789-6700
Dianne K NewmanDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, California, USA dkn@caltech.edu.ORCID 0000-0003-1647-1918
California Institute of Technology · US

Funding

Biological mechanisms and consequences of efficient extracellular electron transfer in Pseudomonas aeruginosaR01AI127850 · NIAID · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI Dianne K Newman · 2017 to 2026
$5.6M
NIAID NIH HHS R01 AI127850
6 · The paper itself

Abstract

Classifying microorganisms as "obligate" aerobes has colloquially implied death without air, leading to the erroneous assumption that, without oxygen, they are unable to survive. However, over the past few decades, more than a few obligate aerobes have been found to possess anaerobic energy conservation strategies that sustain metabolic activity in the absence of growth or at very low growth rates. Similarly, studies emphasizing the aerobic prowess of certain facultative aerobes have sometimes led to underrecognition of their anaerobic capabilities. Yet an inescapable consequence of the affinity both obligate and facultative aerobes have for oxygen is that the metabolism of these organisms may drive this substrate to scarcity, making anoxic survival an essential skill. To illustrate this, we highlight the importance of anaerobic survival strategies for

Indexed as

AerobiosisAnaerobiosisBacterial ProteinsGene Expression Regulation, BacterialOxidation-ReductionOxygenPseudomonas aeruginosaStreptomyces coelicolorBacterial ProteinsOxygenanaerobic metabolismdenitrificationfermentationphenazinesPseudomonas aeruginosasecondary metabolitesStreptomyces coelicolorsurvival physiology

Identifiers

PMID32071098
PMCPMC7221258
OpenAlexW3008663430

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.