Evidence map›Paper›PMID 32071094›Full record

ArticleJournal of bacteriology2020

Intracellular Accumulation of Staphylopine Can Sensitize Staphylococcus aureus to Host-Imposed Zinc Starvation by Chelation-Independent Toxicity.

Kyle P Grim, Jana N Radin, Paola K Párraga Solórzano, Jacqueline R Morey, Katie A Frye, Katherine Ganio, Stephanie L Neville, Christopher A McDevitt, Thomas E Kehl-Fie

Open access · greenAbstract read
In one paragraph

Article in Journal of bacteriology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Analysis of genetic requirements and nutrient availability forbioRxiv : the preprint server for biology · 2024
    Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Kyle P GrimDepartment of Microbiology, University of Illinois Urbana-Champaign, Urbana, Illinois, USA.
Jana N RadinDepartment of Microbiology, University of Illinois Urbana-Champaign, Urbana, Illinois, USA.
Paola K Párraga SolórzanoDepartment of Microbiology, University of Illinois Urbana-Champaign, Urbana, Illinois, USA.
Jacqueline R MoreyDepartment of Microbiology, University of Illinois Urbana-Champaign, Urbana, Illinois, USA.
Katie A FryeDepartment of Microbiology, University of Illinois Urbana-Champaign, Urbana, Illinois, USA.
Katherine GanioDepartment of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia.
Stephanie L NevilleDepartment of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia.
Christopher A McDevittDepartment of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia.ORCID 0000-0003-1596-4841
Thomas E Kehl-FieDepartment of Microbiology, University of Illinois Urbana-Champaign, Urbana, Illinois, USA kehlfie@illinois.edu.ORCID 0000-0001-8234-1113
University of Illinois Urbana-Champaign · USThe University of Melbourne · AUUniversidad de las Fuerzas Armadas ESPE · EC

Funding

Overcoming nutritional immunity: Staphylococcal adaptation to host-imposed manganese and zinc starvationR01AI118880 · NIAID · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI KEHL-FIE, THOMAS EVERETT · 2016 to 2020
$1.9M
NIAID NIH HHS R01 AI118880
6 · The paper itself

Abstract

The host restricts the availability of zinc to prevent infection. To overcome this defense,

Indexed as

AnimalsBacterial ProteinsFemaleHumansImidazolesMiceMice, Inbred C57BLStaphylococcal InfectionsStaphylococcus aureusZincBacterial ProteinsImidazolesstaphylopineZinccalprotectinnutritional immunitypseudopalineStaphylococcus aureusstaphylopinezincophore

Identifiers

PMID32071094
PMCPMC7148132
OpenAlexW3005834789

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.