Evidence map›Paper›PMID 32071081›Full record

ArticleThe Journal of biological chemistry2020

Alexander L Ticho, Pooja Malhotra, Christopher R Manzella, Pradeep K Dudeja, Seema Saksena, Ravinder K Gill, Waddah A Alrefai

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Palmitoylation of solute carriers.Biochemical pharmacology · 2023
    Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Alexander L TichoDepartment of Physiology and Biophysics, College of Medicine, University of Illinois at Chicago, Illinois 60612-7332.
Pooja MalhotraDivision of Gastroenterology and Hepatology, Department of Medicine, College of Medicine, University of Illinois at Chicago, Illinois 60612-7332.
Christopher R ManzellaDepartment of Physiology and Biophysics, College of Medicine, University of Illinois at Chicago, Illinois 60612-7332.
Pradeep K DudejaDivision of Gastroenterology and Hepatology, Department of Medicine, College of Medicine, University of Illinois at Chicago, Illinois 60612-7332.
Seema SaksenaDivision of Gastroenterology and Hepatology, Department of Medicine, College of Medicine, University of Illinois at Chicago, Illinois 60612-7332.
Ravinder K GillDivision of Gastroenterology and Hepatology, Department of Medicine, College of Medicine, University of Illinois at Chicago, Illinois 60612-7332.
Waddah A AlrefaiDivision of Gastroenterology and Hepatology, Department of Medicine, College of Medicine, University of Illinois at Chicago, Illinois 60612-7332 walrefai@uic.edu.
University of Illinois Chicago · USJesse Brown VA Medical Center · US

Funding

Intestinal Anion Transporters: Function and RegulationR01DK054016 · NIDDK · UNIVERSITY OF ILLINOIS AT CHICAGO · PI DUDEJA, PRADEEP K · 1998 to 2022
$7.0M
Transporter Trafficking Mechanisms in Infectious DiarrheaR01DK092441 · NIDDK · UNIVERSITY OF ILLINOIS AT CHICAGO · PI DUDEJA, PRADEEP K · 2011 to 2020
$3.0M
Intestinal 5-HT Transporter: A novel therapeutic target for GI disordersR01DK098170 · NIDDK · UNIVERSITY OF ILLINOIS AT CHICAGO · PI GILL, RAVINDER K · 2014 to 2022
$3.0M
Gut-liver crosstalk in bile-acid induced diarrheaR01DK109709 · NIDDK · UNIVERSITY OF ILLINOIS AT CHICAGO · PI ALREFAI, WADDAH A. · 2016 to 2019
$1.1M
Novel role of serotonin in AhR dependent pathways in intestineF30DK113703 · NIDDK · UNIVERSITY OF ILLINOIS AT CHICAGO · PI MANZELLA, CHRISTOPHER ROBERT · 2017 to 2020
$199k
Epigenetic regulation of bile acids in health and diseaseF30DK117535 · NIDDK · UNIVERSITY OF ILLINOIS AT CHICAGO · PI TICHO, ALEXANDER LOUIS · 2018 to 2020
$150k
BLR&D Research Career Scientist Award ApplicationIK6BX005242 · VA · JESSE BROWN VA MEDICAL CENTER · PI Pradeep K Dudeja · 2020 to 2026
–
Regulation of Intestinal Sodium Absorption in Health and DiseaseI01BX002867 · VA · JESSE BROWN VA MEDICAL CENTER · PI Seema Saksena · 2016 to 2026
–
Mechanisms of Regulation of Intestinal Cl Absorption in IBD Associated DiarrheaI01BX002011 · VA · JESSE BROWN VA MEDICAL CENTER · PI DUDEJA, PRADEEP K · 2013 to 2024
–
Regulation of Intestinal Bile Acid Absorption in Health and Cholesterol-Related DisordersI01BX000152 · VA · JESSE BROWN VA MEDICAL CENTER · PI Waddah A. Alrefai · 2009 to 2026
–
BLRD VA I01 BX000152BLRD VA I01 BX002011BLRD VA I01 BX002867NIDDK NIH HHS F30 DK113703NIDDK NIH HHS F30 DK117535NIDDK NIH HHS R01 DK054016NIDDK NIH HHS R01 DK092441NIDDK NIH HHS R01 DK098170NIDDK NIH HHS R01 DK109709
6 · The paper itself

Abstract

The ileal apical sodium-dependent bile acid transporter (ASBT) is crucial for the enterohepatic circulation of bile acids. ASBT function is rapidly regulated by several posttranslational modifications. One reversible posttranslational modification is

Indexed as

AcylationAcyltransferasesAlkynesBile Acids and SaltsCell MembraneCysteineHEK293 CellsHumansIleumOleic AcidOrganic Anion Transporters, Sodium-DependentPalmitatesSymporters2-bromopalmitateAcyltransferasesAlkynesBile Acids and SaltsCysteineOleic AcidOrganic Anion Transporters, Sodium-DependentPalmitatessodium-bile acid cotransporterSymportersapical sodium-dependent bile acid transporter (ASBT)bile acidbile acid transportileumintestinal epithelial cellsintestinal epitheliumintestinelipid modificationmembrane transportposttranslational modification (PTM)protein acylationS-acylationSLC10A2

Identifiers

PMID32071081
PMCPMC7135972
OpenAlexW3007305569

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.