Evidence map›Paper›PMID 32071059›Full record

ArticleAntimicrobial agents and chemotherapy2020

Whole-Cell Phenotypic Screening of Medicines for Malaria Venture Pathogen Box Identifies Specific Inhibitors of

Alok Tanala Patra, Tejashri Hingamire, Meenakshi A Belekar, Aoli Xiong, Gowtham Subramanian, Zbynek Bozdech, Peter Preiser, Dhanasekaran Shanmugam, Rajesh Chandramohanadas

Open access · greenAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 19 citations in OpenAlex.

  1. Novel drug candidates targetingFrontiers in pharmacology · 2025
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  5. Frontiers in cellular and infection microbiology · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Alok Tanala PatraPillar of Engineering Product Development (EPD), Singapore University of Technology and Design (SUTD), Singapore.ORCID 0000-0001-6983-911X
Tejashri HingamireBiochemical Sciences Division, CSIR National Chemical Laboratory, Pune, India.
Meenakshi A BelekarBiochemical Sciences Division, CSIR National Chemical Laboratory, Pune, India.
Aoli XiongBioSystems and Micromechanics (BioSyM)-IRG, Singapore MIT Alliance for Research & Technology Centre, Singapore.
Gowtham SubramanianPillar of Engineering Product Development (EPD), Singapore University of Technology and Design (SUTD), Singapore.ORCID 0000-0003-1044-6770
Zbynek BozdechSchool of the Biological Sciences, Nanyang Technological University, Singapore.
Peter PreiserSchool of the Biological Sciences, Nanyang Technological University, Singapore.
Dhanasekaran ShanmugamBiochemical Sciences Division, CSIR National Chemical Laboratory, Pune, India d.shanmugam@ncl.res.in rajesh@sutd.edu.sg.ORCID 0000-0002-3341-4846
Rajesh ChandramohanadasPillar of Engineering Product Development (EPD), Singapore University of Technology and Design (SUTD), Singapore d.shanmugam@ncl.res.in rajesh@sutd.edu.sg.ORCID 0000-0002-8760-0396
National Chemical Laboratory · INSingapore University of Technology and Design · SGNanyang Technological University · SGSingapore-MIT Alliance for Research and Technology · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a systematic, cellular phenotype-based antimalarial screening of the Medicines for Malaria Venture Pathogen Box collection, which facilitated the identification of specific blockers of late-stage intraerythrocytic development of

Indexed as

AntimalarialsDNA FragmentationDrug Evaluation, PreclinicalHumansMalaria, FalciparumMerozoitesParasitic Sensitivity TestsPlasmodium falciparumSchizontsTrophozoitesAntimalarialsDNA fragmentationegressMedicines for Malaria VentureMMVPathogen Boxphenotypic screeningPlasmodium falciparumschizontsstage-specific inhibition

Identifiers

PMID32071059
PMCPMC7179631
OpenAlexW3008541488

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.