ArticleParasites & vectors2020
Genetic differentiation and population structure of Anopheles funestus from Uganda and the southern African countries of Malawi, Mozambique, Zambia and Zimbabwe.
Article in Parasites & vectors, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- The genomics of insecticide resistance in Anopheles funestus: insights from a large bed-net trial.BMC genomics · 2026Article
- Article
- Signatures of selection and mechanisms of insecticide resistance in UgandanbioRxiv : the preprint server for biology · 2025Article
- Advances in the genetic characterization of the malaria vector, Anopheles funestus, and implications for improved surveillance and control.Malaria journal · 2023Review
- Fine-scale spatial distribution of deltamethrin resistance and population structure of Anopheles funestus and Anopheles arabiensis populations in Southern Mozambique.Malaria journal · 2023Article
- Article
- Six decades of malaria vector control in southern Africa: a review of the entomological evidence-base.Malaria journal · 2022Review
- Population genetic structure of the malaria vector Anopheles minimus in Thailand based on mitochondrial DNA markers.Parasites & vectors · 2021Article
- CYP6P9-Driven Signatures of Selective Sweep of Metabolic Resistance to Pyrethroids in the Malaria VectorGenes · 2020Article
- Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
backgroundAnopheles funestus (s.s.) is a primary vector of the malaria parasite Plasmodium falciparum in Africa, a human pathogen that causes almost half a million deaths each year. The population structure of An. funestus was examined in samples from Uganda and the southern African countries of Malawi, Mozambique, Zambia and Zimbabwe.
methodsTwelve microsatellites were used to estimate the genetic diversity and differentiation of An. funestus from 13 representative locations across five countries. These were comprised of four sites from Uganda, three from Malawi and two each from Mozambique, Zambia and Zimbabwe.
resultsAll loci were highly polymorphic across the populations with high allelic richness and heterozygosity. A high genetic diversity was observed with 2-19 alleles per locus and an average number of seven alleles. Overall, expected heterozygosity (H
conclusionsHigh genetic diversity revealed by the loci with low to moderate differentiation, identified two clusters among the An. funestus populations. Further research on the population dynamics of An. funestus in east and southern Africa is essential to understand the implications of this structuring and what effect it may have on the efficient implementation of mosquito vector control strategies.
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