Evidence map›Paper›PMID 32070065›Full record

ArticleInternational journal of molecular sciences2020

Characterization of Inhibitory Effectiveness in Hyperpolarization-Activated Cation Currents by a Group of

Ping-Chung Kuo, Yen-Chin Liu, Yi-Ching Lo, Sheng-Nan Wu

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Editorial to the Special Issue "Electrophysiology".International journal of molecular sciences · 2021
    Article
  5. Article
  6. Article
  7. Effectiveness in the Block by Honokiol, a Dimerized Allylphenol fromInternational journal of molecular sciences · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Ping-Chung KuoSchool of Pharmacy, National Cheng Kung University Medical College, Tainan 70101, Taiwan.
Yen-Chin LiuDepartment of Anesthesiology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 70101, Taiwan.
Yi-Ching LoDepartment of Pharmacology, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.
Sheng-Nan WuDepartment of Physiology, National Cheng Kung University Medical College, Tainan 70101, Taiwan.
National Cheng Kung University · TWKaohsiung Medical University · TWNational Cheng Kung University Hospital · TW

Funding

Ministry of Education, Taiwan D108-F2507Ministry of Science and Technology, Taiwan MOST-108-2314-B-006-094National Cheng Kung University, Taiwan D107-F2519 and NCKUH-10709001
6 · The paper itself

Abstract

Croton is an extensive flowering plant genus in the spurge family, Euphorbiaceae. Three croton compounds with the common ent-kaurane skeleton have been purified from

methodsWe examined any modifications of croton components (i.e., croton-01 [ent-18-acetoxy-7α-hydroxykaur-16-en-15-one], croton-02 [ent-7α,14β-dihydroxykaur-16-en-15-one] and croton-03 [ent-1β-acetoxy-7α,14β-dihydroxykaur-16-en-15-one] on either hyperpolarization-activated cation current (I

resultsAddition of croton-01, croton-02, or croton-03 effectively and differentially depressed

conclusionOur study highlights the evidence that these

Indexed as

Adenylyl CyclasesAnimalsCell Line, TumorCrotonDisease Models, AnimalDiterpenes, KauraneGene Expression Regulation, NeoplasticHumansHyperpolarization-Activated Cyclic Nucleotide-Gated ChannelsMolecular StructurePituitary NeoplasmsPlant ExtractsPlant LeavesRatsAdenylyl CyclasesDiterpenes, KauraneHyperpolarization-Activated Cyclic Nucleotide-Gated ChannelsPlant Extractscrotonerg-mediated K+ currenthyperpolarization-activated cation currentmembrane potentialpancreatic β-cellpituitary cell

Identifiers

PMID32070065
PMCPMC7072998
OpenAlexW3006595912

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.