Evidence map›Paper›PMID 32069998›Full record

ReviewInternational journal of environmental research and public health2020

A Detailed Review Study on Potential Effects of Microplastics and Additives of Concern on Human Health.

Claudia Campanale, Carmine Massarelli, Ilaria Savino, Vito Locaputo, Vito Felice Uricchio

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in International journal of environmental research and public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06107933 (Developmental Impacts of MicroPLastics Exposure in Early Life), which is not on this map. Cited by 356 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
356citing papers in PubMed, 9 pooled it
46.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06107933 recruitingnot on this mapstarted 2023, after this paper: background citation

Developmental Impacts of MicroPLastics Exposure in Early Life

TypeobservationalSponsorJohns Hopkins Bloomberg School of Public HealthRan2023 to 2027Enrolled40ConditionsInfant Development, Breast Feeding, Environmental ExposureArmsObservational only
3 · Its place in the literature

Who cites it

356 citing papers in PubMed, 9 syntheses or guidelines pooled it, 1,779 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Impacts of microplastics on gut health: Current status and future directions.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2026
    Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Pooled it
  9. Pooled it
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Microplastics in the Female Genital Tract and Fetoplacental Continuum: A Lesion-Based Framework for Pathophysiological Interpretation.Pathophysiology : the official journal of the International Society for Pathophysiology · 2026
    Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Review

296 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Claudia CampanaleWater Research Institute-Italian National Research Council (IRSA-CNR), Bari, BA, Italy.
Carmine MassarelliWater Research Institute-Italian National Research Council (IRSA-CNR), Bari, BA, Italy.
Ilaria SavinoWater Research Institute-Italian National Research Council (IRSA-CNR), Bari, BA, Italy.
Vito LocaputoWater Research Institute-Italian National Research Council (IRSA-CNR), Bari, BA, Italy.
Vito Felice UricchioWater Research Institute-Italian National Research Council (IRSA-CNR), Bari, BA, Italy.
Water Research Institute · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The distribution and abundance of microplastics into the world are so extensive that many scientists use them as key indicators of the recent and contemporary period defining a new historical epoch: The Plasticene. However, the implications of microplastics are not yet thoroughly understood. There is considerable complexity involved to understand their impact due to different physical-chemical properties that make microplastics multifaceted stressors. If, on the one hand, microplastics carry toxic chemicals in the ecosystems, thus serving as vectors of transport, they are themselves, on the other hand, a cocktail of hazardous chemicals that are added voluntarily during their production as additives to increase polymer properties and prolong their life. To date, there is a considerable lack of knowledge on the major additives of concern that are used in the plastic industry, on their fate once microplastics dispose into the environment, and on their consequent effects on human health when associated with micro and nanoplastics. The present study emphasizes the most toxic and dangerous chemical substances that are contained in all plastic products to describe the effects and implications of these hazardous chemicals on human health, providing a detailed overview of studies that have investigated their abundance on microplastics. In the present work, we conducted a capillary review of the literature on micro and nanoplastic exposure pathways and their potential risk to human health to summarize current knowledge with the intention of better focus future research in this area and fill knowledge gaps.

Indexed as

Environmental HealthMicroplasticsWater Pollutants, ChemicalEcosystemEnvironmental MonitoringHumansRisk AssessmentMicroplasticsWater Pollutants, Chemicaladditiveshuman healthmicroplasticsnanoplastics

Identifiers

PMID32069998
PMCPMC7068600
OpenAlexW3006275595

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.