Evidence map›Paper›PMID 32069954›Full record

ArticleJournal of clinical medicine2020

Evidences for Expression and Location of ANGPTL8 in Human Adipose Tissue.

Leonardo Catalano-Iniesta, Virginia Sánchez Robledo, María Carmen Iglesias-Osma, Amparo Galán Albiñana, Sixto Carrero, Enrique J Blanco, Marta Carretero-Hernández, José Carretero, María José García-Barrado

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Leonardo Catalano-IniestaDepartment of Physiology and Pharmacology, Faculty of Medicine, University of Salamanca, 38007 Salamanca, Spain.
Virginia Sánchez RobledoDepartment of Physiology and Pharmacology, Faculty of Medicine, University of Salamanca, 38007 Salamanca, Spain.
María Carmen Iglesias-OsmaDepartment of Physiology and Pharmacology, Faculty of Medicine, University of Salamanca, 38007 Salamanca, Spain.
Amparo Galán AlbiñanaGene Expression and RNA Metabolism Laboratory, Centro de Investigación Príncipe Felipe (CIPF), C/ E. Primo Yúfera 3, 46012 Valencia, Spain.
Sixto CarreroSurgery Service of University Hospital of Salamanca, 38007 Salamanca, Spain.
Enrique J BlancoLaboratory of Neuroendocrinology, Institute of Neurosciences of Castilla y León (INCyL), and Laboratory of Neuroendocrinology and Obesity, Institute of Biomedical Research of Salamanca (IBSAL), University of Salamanca, 38007 Salamanca, Spain.
Marta Carretero-HernándezDepartment of Human Anatomy and Histology, Faculty of Medicine, University of Salamanca, 38007 Salamanca, Spain.
José CarreteroLaboratory of Neuroendocrinology, Institute of Neurosciences of Castilla y León (INCyL), and Laboratory of Neuroendocrinology and Obesity, Institute of Biomedical Research of Salamanca (IBSAL), University of Salamanca, 38007 Salamanca, Spain.
María José García-BarradoDepartment of Physiology and Pharmacology, Faculty of Medicine, University of Salamanca, 38007 Salamanca, Spain.
Universidad de Salamanca · ESCentro de Investigacion Principe Felipe · ES

Funding

Consejeria de Sanidad, Junta de Castilla y León. Universidad de Salamanca BIO/SA49/14
6 · The paper itself

Abstract

The metabolism of triglycerides (TGs) is regulated, among others, by the lipoprotein lipase (LPL) that hydrolyses the TGs on endothelial cells. In turn, LPL is inhibited by the ANGPTLs family of proteins, such as ANGPTL3, 4, and, 8; the latter is the least known. In this work, we have tried to establish the expression and localisation of the Angiopoietin-like 8 (ANGPTL8) protein in the visceral adipose tissue (VAT) of morbid-obese and non-obese patients. 109 subjects (66 women and 43 men) undergoing laparoscopic surgery participated in this study. A blood sample and a portion of the VAT were obtained, and the patients were classified according to their Body Mass Index (BMI) as non-obese (19.5-30 kg/m

Indexed as

ANGPTL8endothelial cellsobesityvisceral adipose tissue (VAT)

Identifiers

PMID32069954
PMCPMC7074245
OpenAlexW3005922856

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.