Evidence map›Paper›PMID 32069905›Full record

ArticleInternational journal of molecular sciences2020

Exploring the Photodynamic Properties of Two Antiproliferative Benzodiazopyrrole Derivatives.

Concetta Imperatore, Mohammadhassan Valadan, Luciana Tartaglione, Marco Persico, Anna Ramunno, Marialuisa Menna, Marcello Casertano, Carmela Dell'Aversano, Manjot Singh, Maria Luisa d'Aulisio Garigliota and 5 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Kinetic Study ofInternational journal of molecular sciences · 2024
    Article
  3. Article
  4. Article
  5. Article
  6. The Physical Chemistry and Chemical Physics (PCCP) Section of theInternational journal of molecular sciences · 2021
    Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Concetta ImperatoreDepartment of Pharmacy, University of Naples Federico II, 80131 Naples, Italy.ORCID 0000-0001-7377-0653
Mohammadhassan ValadanDepartment of Physics "Ettore Pancini", University of Naples Federico II, 80126 Naples, Italy.ORCID 0000-0001-8656-9510
Luciana TartaglioneDepartment of Pharmacy, University of Naples Federico II, 80131 Naples, Italy.
Marco PersicoDepartment of Pharmacy, University of Naples Federico II, 80131 Naples, Italy.
Anna RamunnoDepartment of Pharmacy/DIFARMA, University of Salerno, 84084 Fisciano, Salerno, Italy.
Marialuisa MennaDepartment of Pharmacy, University of Naples Federico II, 80131 Naples, Italy.ORCID 0000-0002-4515-3014
Marcello CasertanoDepartment of Pharmacy, University of Naples Federico II, 80131 Naples, Italy.ORCID 0000-0001-5037-712X
Carmela Dell'AversanoDepartment of Pharmacy, University of Naples Federico II, 80131 Naples, Italy.ORCID 0000-0001-8337-3029
Manjot SinghDepartment of Physics "Ettore Pancini", University of Naples Federico II, 80126 Naples, Italy.
Maria Luisa d'Aulisio GarigliotaDepartment of Pharmacy/DIFARMA, University of Salerno, 84084 Fisciano, Salerno, Italy.
Francesco BajardiDepartment of Physics "Ettore Pancini", University of Naples Federico II, 80126 Naples, Italy.ORCID 0000-0002-0333-6234
Elena MorelliDepartment of Pharmacy, University of Naples Federico II, 80131 Naples, Italy.
Caterina FattorussoDepartment of Pharmacy, University of Naples Federico II, 80131 Naples, Italy.ORCID 0000-0003-3330-4281
Carlo AltucciDepartment of Physics "Ettore Pancini", University of Naples Federico II, 80126 Naples, Italy.
Michela VarraDepartment of Pharmacy, University of Naples Federico II, 80131 Naples, Italy.
University of Naples Federico II · ITCoNISMa · ITUniversity of Salerno · IT

Funding

Ministero dell'Istruzione, dell'Università e della Ricerca 20173B72NBRegione Campania B61G18000470007
6 · The paper itself

Abstract

The identification of molecules whose biological activity can be properly modulated by light is a promising therapeutic approach aimed to improve drug selectivity and efficacy on the molecular target and to limit the side effects compared to traditional drugs. Recently, two photo-switchable diastereomeric benzodiazopyrrole derivatives

Indexed as

PhotochemotherapyCell ProliferationChromatography, LiquidColorectal NeoplasmsDiazonium CompoundsHCT116 CellsHumansMagnetic Resonance SpectroscopyMass SpectrometryPyrrolesDiazonium CompoundsPyrrolescis-trans conversionconformational analysisDFT optimizationdiazo derivativefast UV spectroscopyLC-HRMSphotoswitchable azoheteroarene

Identifiers

PMID32069905
PMCPMC7072997
OpenAlexW3005727525

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.