ArticlePloS one2020
MicroRNA expression patterns unveil differential expression of conserved miRNAs and target genes against abiotic stress in safflower.
Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 53 citations in OpenAlex.
- MicroRNA regulation and physiological adaptation of Brassica juncea to cadmium toxicity.Molecular biology reports · 2026Article
- Genome-wide identification of the HvSCAMP gene family in barley and functional characterization of the role of HvSCAMP1 in salt tolerance.BMC plant biology · 2026Article
- Genome-wide analysis of Phaseolus vulgaris L. miR172 gene family members under heavy metal stress.BMC genomics · 2026Article
- Physiological response of safflower to water deficit and genome-wide identification of its NAC transcription factor family.Scientific reports · 2025Article
- Non-coding RNAs in plant stress responses: molecular insights and agricultural applications.Plant biotechnology journal · 2025Review
- miR156 Is a Negative Regulator of Aluminum Response inPlants (Basel, Switzerland) · 2025Article
- Integrated analysis of transcriptome, sRNAome, and degradome involved in the drought-response of maize Zhengdan958.Open life sciences · 2025Article
- Functional characterization of protein SUMOylation in the miRNA transcription regulation during heat stress in Arabidopsis.The plant genome · 2024Article
- Article
- Mechanism of action of microRNA166 on nitric oxide in alfalfa (Medicago sativa L.) under drought stress.BMC genomics · 2024Article
- The multifaceted role of RNA-based regulation in plant stress memory.Frontiers in plant science · 2024Review
- Article
- Application of RNAi technology: a novel approach to navigate abiotic stresses.Molecular biology reports · 2022Review
- Molecular Aspects of MicroRNAs and Phytohormonal Signaling in Response to Drought Stress: A Review.Current issues in molecular biology · 2022Review
- Article
- Research on lncRNA related to drought resistance of Shanlan upland rice.BMC genomics · 2022Article
- Early selective strategies for higher yielding bio-economic Indian ginseng based on genotypic study through metabolic and molecular markers.Saudi journal of biological sciences · 2022Article
- Molecular insights into mechanisms underlying thermo-tolerance in tomato.Frontiers in plant science · 2022Review
- microRNA 166: an evolutionarily conserved stress biomarker in land plants targeting HD-ZIP family.Physiology and molecular biology of plants : an international journal of functional plant biology · 2021Review
- Small RNAs: The Essential Regulators in Plant Thermotolerance.Frontiers in plant science · 2021Review
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Environmental stresses influence the growth and development of plants by influencing patterns of gene expression. Different regulators control gene expression, including transcription factors (TFs) and microRNAs. MicroRNAs (miRNAs: ~21 nucleotides long) are encoded by miRNA genes transcribed by RNA polymerase II (RNP-II) and play key roles in plant development and physiology. There is little knowledge currently available on miRNAs and their function in response to environmental stresses in safflower. To obtain more information on safflower miRNAs, we initially used a comparative genomics approach and succeeded in identifying 126 miRNAs belonging to 29 conserved families, along with their target genes. In this study, we investigated the expression profiles of seven conserved miRNAs related to drought, salinity, heat, and Cd stress in the leaf and root organs using qRT-PCR, for the first time. Gene Ontology (GO) analysis found that target genes of miRNAs are often TFs such as AP2/ERF and HD-ZIP as well as NAC domain-containing proteins. Expression analyses confirmed that miRNAs can play a vital role in keeping safflower stress-tolerant. Differential expression of miR156, miR162, miR164, miR166, miR172, miR398, and miR408 regulate the expression of their respective target genes. These genes activate several pathways leading to physiological and biochemical responses to abiotic stresses. Some conserved miRNAs were regulated by abiotic stresses. Our finding provides valuable information to understand miRNAs in relation to different abiotic stresses in safflower.
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