ArticleJAMA2020
Do Polygenic Risk Scores Improve Patient Selection for Prevention of Coronary Artery Disease?
Article in JAMA, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Genome-wide pleiotropy analysis identifies novel blood pressure variants and improves its polygenic risk scores.Genetic epidemiology · 2022Pooled it
- Population genetic considerations for using biobanks as international resources in the pandemic era and beyond.BMC genomics · 2021Pooled it
- Greater value add from electronic health records than polygenic risk scores for predicting myocardial infarction in machine learning.Communications medicine · 2025Article
- Promises and pitfalls of preimplantation genetic testing for polygenic disorders: a narrative review.F&S reviews · 2025Article
- Identifying and characterizing disease subpopulations that most benefit from polygenic risk scores.Scientific reports · 2024Article
- Sex inequalities in cardiovascular risk prediction.Cardiovascular research · 2024Article
- Settling the score: what composite measures of social determinants tell us about hypertension risk.JNCI cancer spectrum · 2024Article
- Effectiveness and feasibility of cardiovascular disease personalized prevention on high polygenic risk score subjects: a randomized controlled pilot study.European heart journal open · 2022Article
- Predictive Utility of a Validated Polygenic Risk Score for Long-Term Risk of Coronary Heart Disease in Young and Middle-Aged Adults.Circulation · 2022Article
- Challenges and Opportunities for Developing More Generalizable Polygenic Risk Scores.Annual review of biomedical data science · 2022Review
- Cardiovascular Risk Assessment Using Artificial Intelligence-Enabled Event Adjudication and Hematologic Predictors.Circulation. Cardiovascular quality and outcomes · 2022Article
- Commentary: Polygenic risk for breast cancer: in search for potential clinical utility.International journal of epidemiology · 2022Article
- Novel strategy for disease risk prediction incorporating predicted gene expression and DNA methylation data: a multi-phased study of prostate cancer.Cancer communications (London, England) · 2021Article
- Genomic risk prediction of coronary artery disease in women with breast cancer: a prospective cohort study.Breast cancer research : BCR · 2021Article
- Polygenic Risk Scores to Identify CVD Risk and Tailor Therapy: Hope or Hype?Current atherosclerosis reports · 2021Review
- Body Mass Index and Birth Weight Improve Polygenic Risk Score for Type 2 Diabetes.Journal of personalized medicine · 2021Article
- How Do We Incorporate Polygenic Risk Scores in Cardiovascular Disease Risk Assessment and Management?Current atherosclerosis reports · 2021Review
- Predictive Added Value of Selected Plasma Lipids to a Re-estimated Minimal Risk Tool.Frontiers in cardiovascular medicine · 2021Article
- A Journey through Genetic Architecture and Predisposition of Coronary Artery Disease.Current genomics · 2020Review
- An Outbreak of Polygenic Scores for Coronary Artery Disease.Journal of the American College of Cardiology · 2020Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
32068803What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.