Evidence map›Paper›PMID 32068528›Full record

ArticleThe Journal of general virology2020

West Nile Virus fidelity modulates the capacity for host cycling and adaptation.

Haley S Caldwell, Kiet Ngo, Janice D Pata, Laura D Kramer, Alexander T Ciota

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of general virology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Haley S CaldwellThe Arbovirus Laboratory, Wadsworth Center, New York State Department of Health, Slingerlands, NY, USA.
Kiet NgoThe Arbovirus Laboratory, Wadsworth Center, New York State Department of Health, Slingerlands, NY, USA.
Janice D PataDepartment of Biomedical Sciences, State University of New York at Albany School of Public Health, Albany, NY, USA.
Laura D KramerThe Arbovirus Laboratory, Wadsworth Center, New York State Department of Health, Slingerlands, NY, USA.
Alexander T CiotaThe Arbovirus Laboratory, Wadsworth Center, New York State Department of Health, Slingerlands, NY, USA.
New York State Department of Health · USUniversity at Albany, State University of New York · US

Funding

Evaluating the consequences of genotype displacement and geographic bias of West Nile virus in New York StateR21AI146856 · NIAID · WADSWORTH CENTER · PI CIOTA, ALEXANDER TIMOTHY · 2020 to 2021
$378k
NIAID NIH HHS R21 AI146856
6 · The paper itself

Abstract

The fidelity of flaviviruses is thought to be tightly regulated for optimal fitness within and between hosts. West Nile virus (WNV) high-fidelity (HiFi) mutations V793I and G806R within the RNA-dependent RNA polymerase, and low-fidelity (LoFi) mutation T248I within the methyltransferase, were previously shown to attenuate infectivity and replicative fitness in

Indexed as

Adaptation, PhysiologicalAnimalsBirdsCell LineComputational BiologyCulicidaeDucksHost Microbial InteractionsMutationQuasispeciesRNA-Dependent RNA PolymeraseSerial PassageViral Envelope ProteinsVirus ReplicationWest Nile virusRNA-Dependent RNA PolymeraseViral Envelope Proteinsfidelityflavivirushost cyclingquasispeciesviral fitnessWest Nile virus

Identifiers

PMID32068528
PMCPMC7414436
OpenAlexW3007599245

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.